INT119522

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Context Info
Confidence 0.60
First Reported 2004
Last Reported 2004
Negated 0
Speculated 0
Reported most in Abstract
Documents 1
Total Number 2
Disease Relevance 2.34
Pain Relevance 1.39

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

peptidase activity (Prss12)
Prss12 (Rattus norvegicus)
Pain Link Frequency Relevance Heat
antinociception 14 96.96 Very High Very High Very High
analgesia 2 96.48 Very High Very High Very High
opioid receptor 2 95.60 Very High Very High Very High
antagonist 4 88.48 High High
medulla 2 86.16 High High
Hyperalgesia 4 33.76 Quite Low
Visceral pain 2 27.60 Quite Low
nociceptor 2 25.00 Low Low
Disease Link Frequency Relevance Heat
Stress 10 99.98 Very High Very High Very High
Nociception 16 93.28 High High
Targeted Disruption 4 77.04 Quite High
Irritable Bowel Syndrome /

Irritable Bowel Syndrome Super

2 66.48 Quite High
Hyperalgesia 6 43.92 Quite Low
Irritable Bowel Syndrome /

Irritable Bowel Syndrome Super / Visceral Pain

2 5.00 Very Low Very Low Very Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
Furthermore, intense stress results in increased NT expression in several hypothalamic nuclei that have been implicated in stress-induced antinociception (SIAN); however, there is little direct evidence that endogenous NT is required for SIAN.
Positive_regulation (results) of Gene_expression (expression) of NT associated with stress and antinociception
1) Confidence 0.60 Published 2004 Journal Neuroscience Section Abstract Doc Link 15207335 Disease Relevance 1.11 Pain Relevance 0.70
Furthermore, intense stress results in increased NT expression in several hypothalamic nuclei that have been implicated in stress-induced antinociception (SIAN); however, there is little direct evidence that endogenous NT is required for SIAN.
Positive_regulation (increased) of Gene_expression (expression) of NT associated with stress and antinociception
2) Confidence 0.40 Published 2004 Journal Neuroscience Section Abstract Doc Link 15207335 Disease Relevance 1.10 Pain Relevance 0.70

General Comments

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