INT119564

Context Info Confidence 0.00 First Reported 2004 Last Reported 2004 Negated 0 Speculated 0 Reported most in Abstract Documents 1 Total Number 1 Disease Relevance 0.68 Pain Relevance 0.16

endosome (CD1D) extracellular space (IL5) extracellular region (IL5) histone binding (CD1D) plasma membrane (CD1D) nucleus (TLE4)

Anatomy Link Frequency mast cells 2 TLE4 (Homo sapiens) CD1D (Homo sapiens) IL5 (Homo sapiens)

Pain Link Frequency Relevance Heat cytokine 1 89.60 Inflammation 1 74.80 Pain 1 74.12

Disease Link Frequency Relevance Heat Leukemia 1 100.00 Hypersensitivity 4 96.00 Anaphylaxis 1 94.12 INFLAMMATION 1 74.80 Pain 1 74.12

Sentences Mentioned In

Key:

Protein

Mutation

Event

Anatomy

Negation

Speculation

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Disease term

In addition, BCE inhibited the IL-4, IL-5 and TNF-alpha mRNA induction by PMA and A23187 in human leukemia mast cells, HMC-1.

BCE Negative_regulation (inhibited) of HMC-1 Positive_regulation (induction) of IL-5 in mast cells associated with leukemia

1) Confidence 0.00 Published 2004 Journal Immunopharmacol Immunotoxicol Section Abstract Doc Link 15209365 Disease Relevance 0.68 Pain Relevance 0.16

General Comments

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