INT119675

Context Info Confidence 0.32 First Reported 2004 Last Reported 2004 Negated 0 Speculated 0 Reported most in Abstract Documents 1 Total Number 1 Disease Relevance 0.43 Pain Relevance 0.30

cell differentiation (GLI2) cell proliferation (GLI2) nucleus (GLI2) intracellular (GLI2) cilium (GLI2) cytoplasm (GLI2)

Anatomy Link Frequency SH-SY5Y 2 GLI2 (Homo sapiens)

Pain Link Frequency Relevance Heat cINOD 3 91.08 Abeta 1 89.20

Disease Link Frequency Relevance Heat Neuroblastoma 1 98.64 Alzheimer's Dementia 1 88.40 Disease 1 83.20 INFLAMMATION 1 81.68 Drug Induced Neurotoxicity 1 75.00

Sentences Mentioned In

Key:

Protein

Mutation

Event

Anatomy

Negation

Speculation

Pain term

Disease term

We compared the neuroprotective activity of S- and R-enantiomers of flurbiprofen and ibuprofen in a standard assay where secretions from activated human THP-1 or microglial cells are toxic to neuroblastoma SH-SY5Y cells.

Positive_regulation (activated) of Localization (secretions) of THP-1 in SH-SY5Y associated with neuroblastoma

1) Confidence 0.32 Published 2004 Journal J. Neuroimmunol. Section Abstract Doc Link 15223239 Disease Relevance 0.43 Pain Relevance 0.30

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