INT119719

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Context Info
Confidence 0.49
First Reported 2002
Last Reported 2011
Negated 0
Speculated 0
Reported most in Body
Documents 3
Total Number 3
Disease Relevance 1.67
Pain Relevance 0.09

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

cytosol (CBL) plasma membrane (CBL) nucleus (CBL)
ligase activity (CBL) cytoplasm (CBL) signal transducer activity (CBL)
Anatomy Link Frequency
B12 1
CBL (Homo sapiens)
Pain Link Frequency Relevance Heat
anesthesia 1 94.80 High High
Glutamate 2 5.00 Very Low Very Low Very Low
Arthritis 2 5.00 Very Low Very Low Very Low
Migraine 1 5.00 Very Low Very Low Very Low
palliative 1 5.00 Very Low Very Low Very Low
Central nervous system 1 5.00 Very Low Very Low Very Low
Inflammation 1 5.00 Very Low Very Low Very Low
Pain 1 5.00 Very Low Very Low Very Low
Neurotransmitter 1 5.00 Very Low Very Low Very Low
headache 1 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
Carcinoma 95 99.84 Very High Very High Very High
Diabetes Mellitus 22 94.32 High High
Adhesions 9 90.80 High High
Disease 34 85.04 High High
Cancer 55 83.08 Quite High
Spinal Cord Diseases 2 75.00 Quite High
Renal Cancer 18 64.56 Quite High
Parkinson's Disease 2 48.72 Quite Low
Metabolic Syndrome 1 47.64 Quite Low
Retinal Diseases 1 46.68 Quite Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
By inactivating cobalamin (Cbl) (vitamin B12), N2O can cause neurologic and hematologic manifestations.
Positive_regulation (inactivating) of Cbl in B12
1) Confidence 0.49 Published 2004 Journal J Neuroimaging Section Abstract Doc Link 15228771 Disease Relevance 0.07 Pain Relevance 0.09
Db/db mice lack a functioning leptin receptor resulting in defective leptin-mediated signal transduction.
Positive_regulation (mediated) of signal transduction
2) Confidence 0.03 Published 2011 Journal Journal of Biomedicine and Biotechnology Section Body Doc Link PMC2948926 Disease Relevance 0.27 Pain Relevance 0
Almost twice as many genes in Signal Transduction were increased in CC compared to Chr; a similar number were decreased in both types.
Positive_regulation (increased) of Transduction associated with carcinoma
3) Confidence 0.01 Published 2002 Journal BMC Bioinformatics Section Body Doc Link PMC130042 Disease Relevance 1.32 Pain Relevance 0

General Comments

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