INT119767

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Context Info
Confidence 0.49
First Reported 2003
Last Reported 2010
Negated 0
Speculated 0
Reported most in Body
Documents 4
Total Number 4
Disease Relevance 1.42
Pain Relevance 1.09

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

cell adhesion (Itgam) nucleus (Itgam)
Anatomy Link Frequency
brain 2
blood cells 2
Itgam (Rattus norvegicus)
Pain Link Frequency Relevance Heat
Inflammation 55 99.92 Very High Very High Very High
Thalamus 12 98.08 Very High Very High Very High
projection neuron 2 90.48 High High
cytokine 12 87.28 High High
medulla 1 79.16 Quite High
Spinal cord 18 78.72 Quite High
glial activation 3 75.00 Quite High
Hyperalgesia 1 63.16 Quite High
allodynia 1 62.48 Quite High
central sensitization 1 60.64 Quite High
Disease Link Frequency Relevance Heat
INFLAMMATION 64 99.92 Very High Very High Very High
Adhesions 42 87.76 High High
Nervous System Injury 8 72.20 Quite High
Hypersensitivity 10 71.44 Quite High
Hyperalgesia 1 63.16 Quite High
Neuropathic Pain 1 62.48 Quite High
Infection 5 44.48 Quite Low
Injury 15 5.00 Very Low Very Low Very Low
Death 8 5.00 Very Low Very Low Very Low
Asthma 6 5.00 Very Low Very Low Very Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
Increased immunoreactivity for OX-42 (CR3/CD11b) and GFAP at various brain regions was also observed after the acute and subacute phases of the inflammation, respectively.
Positive_regulation (Increased) of CD11b Binding (immunoreactivity) of in brain associated with inflammation
1) Confidence 0.49 Published 2004 Journal Eur. J. Neurosci. Section Abstract Doc Link 15233755 Disease Relevance 1.01 Pain Relevance 0.81
However, in all these rats there was markedly increased immunoreactivity for CD11b or ?
Positive_regulation (increased) of CD11b Binding (immunoreactivity) of
2) Confidence 0.26 Published 2010 Journal BMC Neurosci Section Body Doc Link PMC2829570 Disease Relevance 0.08 Pain Relevance 0.24
The binding of CD11b on blood cells was increased 1.8 fold by the antigen, whereas on peritoneal cells the increase was only 1.2 fold.
Positive_regulation (increased) of CD11b Binding (binding) of in blood cells
3) Confidence 0.13 Published 2003 Journal BMC Immunol Section Body Doc Link PMC152650 Disease Relevance 0.14 Pain Relevance 0.04
The histograms, in Figure 4A, show the increase in fluorescence intensity over the control responses upon the addition of PAF, as well as the inhibitory effect of feG on PAF enhancement of CD11b antibody binding.
Positive_regulation (enhancement) of CD11b Binding (binding) of
4) Confidence 0.13 Published 2003 Journal BMC Immunol Section Body Doc Link PMC152650 Disease Relevance 0.19 Pain Relevance 0

General Comments

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