INT119962

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Context Info
Confidence 0.45
First Reported 2004
Last Reported 2010
Negated 0
Speculated 2
Reported most in Body
Documents 2
Total Number 4
Disease Relevance 3.24
Pain Relevance 0.81

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

extracellular space (Crp)
Crp (Mus musculus)
Pain Link Frequency Relevance Heat
Infliximab 34 99.72 Very High Very High Very High
imagery 41 98.52 Very High Very High Very High
beta blocker 4 86.08 High High
spinal inflammation 43 75.76 Quite High
Inflammation 23 67.12 Quite High
ischemia 2 60.04 Quite High
cva 3 50.64 Quite High
Calcium channel 2 47.52 Quite Low
Inflammatory marker 4 39.68 Quite Low
Clonidine 2 25.00 Low Low
Disease Link Frequency Relevance Heat
Left Ventricular Hypertrophy 2 100.00 Very High Very High Very High
Stress 2 99.44 Very High Very High Very High
Hyperkalemia 2 95.76 Very High Very High Very High
Anaphylaxis 2 94.64 High High
Hypertension 14 90.36 High High
Chronic Renal Failure 16 88.04 High High
Renal Disease 2 87.80 High High
Anaemia 2 86.72 High High
Cardiovascular Disease 36 82.04 Quite High
Low Back Pain 33 75.76 Quite High

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
Angiotensin-converting enzyme (ACE) inhibitors and angiotensin II receptor blockers may decrease morbidity and mortality by reducing the mean arterial pressure (MAP), aortic pulse wave velocity, and aortic systolic pressure augmentation, as well as left ventricular hypertrophy (LVH) and probably reduction of C-reactive protein (CRP) and oxidant stress.
Spec (probably) Negative_regulation (reducing) of Negative_regulation (reduction) of C-reactive protein associated with stress and left ventricular hypertrophy
1) Confidence 0.45 Published 2004 Journal Semin Dial Section Abstract Doc Link 15250920 Disease Relevance 1.04 Pain Relevance 0.08
Angiotensin-converting enzyme (ACE) inhibitors and angiotensin II receptor blockers may decrease morbidity and mortality by reducing the mean arterial pressure (MAP), aortic pulse wave velocity, and aortic systolic pressure augmentation, as well as left ventricular hypertrophy (LVH) and probably reduction of C-reactive protein (CRP) and oxidant stress.
Spec (probably) Negative_regulation (reducing) of Negative_regulation (reduction) of CRP associated with stress and left ventricular hypertrophy
2) Confidence 0.33 Published 2004 Journal Semin Dial Section Abstract Doc Link 15250920 Disease Relevance 1.04 Pain Relevance 0.08
Thus, in the infliximab group, early decreases in IL-6 and later decreases in CRP were associated with improvement in MRI activity scores.
Negative_regulation (decreases) of Negative_regulation (decreases) of CRP associated with infliximab and imagery
3) Confidence 0.17 Published 2008 Journal Annals of the Rheumatic Diseases Section Body Doc Link PMC2564765 Disease Relevance 0.41 Pain Relevance 0.60
In model 2, variables of model 1 plus CPC were entered; in model 3, variables of model 1 plus hsCRP were entered; in model 4, variables of model 1 plus CPC and hsCRP were entered simultaneously.
Negative_regulation (entered) of Negative_regulation (variables) of hsCRP
4) Confidence 0.05 Published 2010 Journal PLoS ONE Section Body Doc Link PMC2901328 Disease Relevance 0.76 Pain Relevance 0.06

General Comments

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