From wiki-pain
Jump to: navigation, search
Context Info
Confidence 0.00
First Reported 2004
Last Reported 2004
Negated 0
Speculated 0
Reported most in Abstract
Documents 1
Total Number 1
Disease Relevance 0.99
Pain Relevance 0.70

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

extracellular region (IL8, Prap1) signal transduction (IL8) extracellular space (IL8)
intracellular (IL8)
IL8 (Homo sapiens)
Prap1 (Rattus norvegicus)
Pain Link Frequency Relevance Heat
chemokine 1 99.18 Very High Very High Very High
Inflammation 2 96.08 Very High Very High Very High
cINOD 4 88.32 High High
Paracetamol 5 87.88 High High
aspirin 1 83.52 Quite High
cytokine 1 38.88 Quite Low
COX2 1 25.00 Low Low
Inflammatory stimuli 1 25.00 Low Low
Disease Link Frequency Relevance Heat
Ovarian Cancer 8 99.84 Very High Very High Very High
INFLAMMATION 3 96.08 Very High Very High Very High
Apoptosis 1 94.64 High High
Colon Cancer 1 84.56 Quite High
Frailty 1 76.00 Quite High
Malignant Neoplastic Disease 1 62.32 Quite High
Cancer 1 5.00 Very Low Very Low Very Low
Toxicity 1 5.00 Very Low Very Low Very Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
It is proposed that the major mechanism by these anti-inflammatory agents is a shared pathway dependent on the suppression of NF-kappaB activity, which may subsequently decrease transcription of growth factors, chemokines and proteases such as COX-2, VEGF, IL-8/CXCL8, MCP-1/CCL-2, MIP1alpha/CCL-3, tPA and uPA, which are shown to be elevated in ovarian carcinoma, and which play diverse roles such as inducing angiogenesis, invasion, autocrine growth loops and resistance to apoptosis.
CXCL8 Positive_regulation (elevated) of uPA associated with chemokine, inflammation, ovarian cancer and apoptosis
1) Confidence 0.00 Published 2004 Journal Neoplasma Section Abstract Doc Link 15254653 Disease Relevance 0.99 Pain Relevance 0.70

General Comments

This test has worked.

Personal tools