INT120054

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Context Info
Confidence 0.44
First Reported 2004
Last Reported 2009
Negated 0
Speculated 0
Reported most in Body
Documents 2
Total Number 2
Disease Relevance 0.97
Pain Relevance 0.59

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

mitochondrion (Tspo) aging (Tspo) response to stress (Tspo)
Anatomy Link Frequency
neurons 2
Tspo (Rattus norvegicus)
Pain Link Frequency Relevance Heat
dorsal root ganglion 6 93.24 High High
Spinal cord 1 91.88 High High
Dorsal horn 1 91.12 High High
Sciatic nerve 3 82.56 Quite High
agonist 6 66.96 Quite High
positron emission tomography 52 62.96 Quite High
imagery 9 62.64 Quite High
neuralgia 1 25.00 Low Low
medulla 30 5.00 Very Low Very Low Very Low
Hippocampus 5 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
Ganglion Cysts 6 93.24 High High
Injury 7 89.88 High High
Neurological Disease 11 88.08 High High
Neurodegenerative Disease 3 51.04 Quite High
Herpes Simplex Encephalitis 41 40.36 Quite Low
Cold Sores 22 5.00 Very Low Very Low Very Low
Urological Neuroanatomy 6 5.00 Very Low Very Low Very Low
Disease 6 5.00 Very Low Very Low Very Low
INFLAMMATION 4 5.00 Very Low Very Low Very Low
Demyelinating Disease 2 5.00 Very Low Very Low Very Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
No non-neuronal PBR expression is detected, unlike its putative endogenous ligand the diazepam binding inhibitor (DBI), which is expressed only in non-neuronal cells, including the satellite cells that surround DRG neurons.
Regulation (detected) of Gene_expression (expression) of PBR in neurons associated with dorsal root ganglion
1) Confidence 0.44 Published 2004 Journal Eur. J. Neurosci. Section Abstract Doc Link 15255978 Disease Relevance 0.83 Pain Relevance 0.46
This tracer appears to be a more sensitive tool to detect small changes in TSPO expression than [11C]-(R)-PK11195.
Regulation (changes) of Gene_expression (expression) of TSPO
2) Confidence 0.26 Published 2009 Journal Mol Imaging Biol Section Body Doc Link PMC2763079 Disease Relevance 0.14 Pain Relevance 0.13

General Comments

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