INT120057

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Context Info
Confidence 0.28
First Reported 2004
Last Reported 2004
Negated 1
Speculated 0
Reported most in Abstract
Documents 1
Total Number 1
Disease Relevance 0.14
Pain Relevance 0.78

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small molecule metabolic process (PTGS2) endoplasmic reticulum (PTGS2) enzyme binding (PTGS2)
protein complex (PTGS2) cytoplasm (PTGS2) lipid binding (PTGS2)
PTGS2 (Homo sapiens)
Pain Link Frequency Relevance Heat
cINOD 8 99.30 Very High Very High Very High
aspirin 1 96.76 Very High Very High Very High
Paracetamol 1 94.64 High High
Disease Link Frequency Relevance Heat
INFLAMMATION 2 75.00 Quite High

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
Various types of NSAIDs used in this study showed similar effects on the changes in PGD(2) release and PGHS-2 protein amounts, except those on PGHS activity in cell homogenates; while indomethacin, aspirin, and NS-398 inhibited it, but nimesulide and acetaminophen did not.
Neg (except) Regulation (effects) of Localization (release) of PGHS-2 protein associated with aspirin, paracetamol and cinod
1) Confidence 0.28 Published 2004 Journal Biol. Pharm. Bull. Section Abstract Doc Link 15256727 Disease Relevance 0.14 Pain Relevance 0.78

General Comments

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