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Context Info
Confidence 0.18
First Reported 2004
Last Reported 2004
Negated 0
Speculated 0
Reported most in Abstract
Documents 1
Total Number 1
Disease Relevance 0.76
Pain Relevance 0.55

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

signal transduction (Tlr4, Tnf) plasma membrane (Tlr4, Tnf) intracellular (Tlr4, Tnf)
cell proliferation (Tnf) extracellular space (Tnf) extracellular region (Tnf)
Tlr4 (Mus musculus)
Tnf (Mus musculus)
Pain Link Frequency Relevance Heat
Morphine 1 86.72 High High
antagonist 4 80.96 Quite High
Opioid 3 80.52 Quite High
opioid receptor 1 63.16 Quite High
opiate 1 57.28 Quite High
narcan 1 55.84 Quite High
cytokine 1 44.72 Quite Low
Disease Link Frequency Relevance Heat
Sepsis 4 100.00 Very High Very High Very High
Shock 2 82.44 Quite High
Cancer 2 75.00 Quite High
Necrosis 2 75.00 Quite High
Bacterial Infection 1 75.00 Quite High
Pressure Volume 2 Under Development 1 58.12 Quite High
Death 1 53.84 Quite High
Injury 1 51.40 Quite High

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
These results suggest that naltrexone is capable of preventing LPS-induced septic shock mortality by indirect inhibition of TNF-alpha production in vivo.
LPS Negative_regulation (inhibition) of Gene_expression (production) of TNF-alpha associated with sepsis
1) Confidence 0.18 Published 2004 Journal Brain Behav. Immun. Section Abstract Doc Link 15265541 Disease Relevance 0.76 Pain Relevance 0.55

General Comments

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