INT120189

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Context Info
Confidence 0.75
First Reported 2003
Last Reported 2007
Negated 0
Speculated 0
Reported most in Abstract
Documents 3
Total Number 3
Disease Relevance 0.52
Pain Relevance 0.54

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

cytoskeletal protein binding (Pdlim3) biological_process (Pdlim3) cytoplasm (Pdlim3)
Anatomy Link Frequency
liver 1
Pdlim3 (Rattus norvegicus)
Pain Link Frequency Relevance Heat
Glutamate 4 100.00 Very High Very High Very High
Paracetamol 4 97.44 Very High Very High Very High
anesthesia 3 5.00 Very Low Very Low Very Low
ketamine 2 5.00 Very Low Very Low Very Low
Spinal cord 1 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
Hepatotoxicity 6 99.46 Very High Very High Very High
Adhesions 4 29.72 Quite Low
Injury 3 5.00 Very Low Very Low Very Low
Ganglion Cysts 3 5.00 Very Low Very Low Very Low
Hypothermia 2 5.00 Very Low Very Low Very Low
Proliferative Vitreoretinopathy 1 5.00 Very Low Very Low Very Low
Death 1 5.00 Very Low Very Low Very Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
The liver damage was evidenced by elevated levels of serum glutamate oxaloacetate transaminase (SGOT), serum glutamate pyruvate transaminase (SGPT) and serum alkaline phosphatase (ALP) and hepatic thiobarbituric acid reacting substances (TBARS) and superoxide dismutase (SOD).
Gene_expression (levels) of ALP in liver associated with glutamate and hepatotoxicity
1) Confidence 0.75 Published 2003 Journal Indian J. Physiol. Pharmacol. Section Abstract Doc Link 15266956 Disease Relevance 0.28 Pain Relevance 0.29
HV pretreatment (0.5 and 1.0 ml/kg, p.o.) significantly (P < 0.001) reduced CCl4 or PC-induced elevations of the levels of SGOT, SGPT, ALP and TBARS, while the reduced concentration of SOD due to CCl4 or PC was reversed.
Gene_expression (levels) of ALP
2) Confidence 0.58 Published 2003 Journal Indian J. Physiol. Pharmacol. Section Abstract Doc Link 15266956 Disease Relevance 0.24 Pain Relevance 0.25
The Sap97 spots represent the PDZ domain 3 of Sap97.
Gene_expression (represent) of PDZ domain 3
3) Confidence 0.09 Published 2007 Journal Molecular Vision Section Body Doc Link PMC2610370 Disease Relevance 0 Pain Relevance 0

General Comments

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