INT120239

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Context Info
Confidence 0.65
First Reported 2004
Last Reported 2010
Negated 0
Speculated 1
Reported most in Abstract
Documents 3
Total Number 4
Disease Relevance 1.01
Pain Relevance 0.72

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

nucleolus (NFIB) nucleus (NFIB) intracellular (NFIB)
DNA binding (NFIB)
Anatomy Link Frequency
endothelial cells 2
plasma 1
NFIB (Homo sapiens)
Pain Link Frequency Relevance Heat
antagonist 2 97.28 Very High Very High Very High
aspirin 12 95.92 Very High Very High Very High
cINOD 2 88.84 High High
Inflammation 2 86.48 High High
chemokine 2 77.56 Quite High
cytokine 4 50.00 Quite Low
palliative 1 5.00 Very Low Very Low Very Low
fibrosis 1 5.00 Very Low Very Low Very Low
Pain 1 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
INFLAMMATION 4 88.60 High High
Disease 17 85.44 High High
Diabetes Mellitus 2 84.72 Quite High
Increased Venous Pressure Under Development 4 83.24 Quite High
Prostate Cancer 53 50.00 Quite Low
Cancer 49 34.44 Quite Low
Metastasis 18 5.00 Very Low Very Low Very Low
Apoptosis 8 5.00 Very Low Very Low Very Low
Hypersensitivity 4 5.00 Very Low Very Low Very Low
Hyperplasia 2 5.00 Very Low Very Low Very Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
METHODS: In 265 consecutive primary health care patients (174 women and 91 men), we examined self-rated and physician-rated health, circulating levels of interleukin (IL)-1beta, IL-1 receptor antagonist (IL-1ra), IL-6, and tumor necrosis factor (TNF)-alpha as determined from plasma samples using high-sensitivity enzyme-linked immunoassay.
Gene_expression (levels) of 1beta in plasma
1) Confidence 0.65 Published 2004 Journal Psychosom Med Section Body Doc Link 15272103 Disease Relevance 0 Pain Relevance 0
The few AR target genes that were differentially expressed in PC346Flu1 include EHF, NFIB and HLX, which are involved in development and differentiation processes.
Gene_expression (expressed) of NFIB
2) Confidence 0.43 Published 2010 Journal PLoS ONE Section Body Doc Link PMC2957443 Disease Relevance 0 Pain Relevance 0.05
To test this assumption, as well as the possible mechanisms involved, the MCP-1 expression and secretion, the reactive oxygen species levels, nuclear factor-kB (NF-kB) and activator protein-1 (AP-1) expression were determined in human endothelial cells exposed to high glucose concentrations in the presence of aspirin, fenofibrate and clofibrate.
Gene_expression (expression) of nuclear factor-kB in endothelial cells associated with aspirin
3) Confidence 0.13 Published 2006 Journal Vascul. Pharmacol. Section Abstract Doc Link 16600694 Disease Relevance 0.50 Pain Relevance 0.33
To test this assumption, as well as the possible mechanisms involved, the MCP-1 expression and secretion, the reactive oxygen species levels, nuclear factor-kB (NF-kB) and activator protein-1 (AP-1) expression were determined in human endothelial cells exposed to high glucose concentrations in the presence of aspirin, fenofibrate and clofibrate.
Spec (determined) Gene_expression (expression) of nuclear factor-kB in endothelial cells associated with aspirin
4) Confidence 0.10 Published 2006 Journal Vascul. Pharmacol. Section Abstract Doc Link 16600694 Disease Relevance 0.51 Pain Relevance 0.34

General Comments

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