INT120247

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Context Info
Confidence 0.48
First Reported 2004
Last Reported 2011
Negated 1
Speculated 0
Reported most in Body
Documents 3
Total Number 3
Disease Relevance 2.39
Pain Relevance 0.10

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

nucleus (FOXE1) DNA binding (FOXE1) transcription factor binding (FOXE1)
Anatomy Link Frequency
Thyroid 1
smooth muscle 1
FOXE1 (Homo sapiens)
Pain Link Frequency Relevance Heat
cva 2 79.20 Quite High
Angina 2 64.52 Quite High
Thoracotomy 1 49.60 Quite Low
Pain 2 5.00 Very Low Very Low Very Low
iatrogenic 1 5.00 Very Low Very Low Very Low
cINOD 1 5.00 Very Low Very Low Very Low
Inflammation 1 5.00 Very Low Very Low Very Low
melanocortin 1 receptor 1 5.00 Very Low Very Low Very Low
headache 1 5.00 Very Low Very Low Very Low
nud 1 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
Cancer 64 99.90 Very High Very High Very High
Gastrointestinal Stromal Tumor 11 92.72 High High
Skin Cancer 70 91.88 High High
Apoptosis 2 89.36 High High
Hemorrhage 3 79.20 Quite High
Necrosis 4 78.64 Quite High
Lung Cancer 2 75.00 Quite High
Small Cell Lung Cancer 1 71.52 Quite High
Genetic Predisposition To Disease 1 66.72 Quite High
Dyspnea 3 65.32 Quite High

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
The morules showed positive thyroid transcription factor-1 staining, weak keratin staining, and negative staining for smooth muscle actin, desmin, and HMB-45.
Gene_expression (staining) of thyroid transcription factor-1 in smooth muscle
1) Confidence 0.48 Published 2004 Journal Am. J. Clin. Pathol. Section Abstract Doc Link 15272538 Disease Relevance 0.88 Pain Relevance 0.10
Furthermore, contributions of the FOX gene family, in particular FOXM1 and FOXE1, appear to be involved in downstream signalling [35–38].
Gene_expression (contributions) of FOXE1
2) Confidence 0.17 Published 2011 Journal Journal of Skin Cancer Section Body Doc Link PMC3021865 Disease Relevance 0.83 Pain Relevance 0
The tumor was negative for S 100 protein CD 99, Thyroid transcription factor (TTF 2) and calretinin.
Neg (negative) Gene_expression (negative) of Thyroid transcription factor in Thyroid associated with cancer
3) Confidence 0.02 Published 2008 Journal J Cardiothorac Surg Section Body Doc Link PMC2409332 Disease Relevance 0.68 Pain Relevance 0

General Comments

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