INT120293

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Context Info
Confidence 0.04
First Reported 2004
Last Reported 2004
Negated 0
Speculated 0
Reported most in Abstract
Documents 1
Total Number 1
Disease Relevance 0.14
Pain Relevance 0.86

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

nucleoplasm (RYBP) ATPase activity (Abcc2) nucleus (RYBP)
intracellular (RYBP) DNA binding (RYBP) cytoplasm (RYBP)
Anatomy Link Frequency
liver 1
RYBP (Homo sapiens)
Abcc2 (Rattus norvegicus)
Pain Link Frequency Relevance Heat
Paracetamol 11 100.00 Very High Very High Very High
Disease Link Frequency Relevance Heat
Stress 2 86.52 High High
Body Weight 1 53.92 Quite High

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
Because specific APAP-conjugated metabolites are Mrp2 substrates, we postulate that induction of Mrp2 by APAP may represent an adaptive mechanism to accelerate liver disposition of the drug.
APAP Positive_regulation (induction) of Mrp2 in liver associated with paracetamol
1) Confidence 0.04 Published 2004 Journal Biochem. Pharmacol. Section Abstract Doc Link 15276087 Disease Relevance 0.14 Pain Relevance 0.86

General Comments

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