INT120349

From wiki-pain
Jump to: navigation, search
Context Info
Confidence 0.05
First Reported 2004
Last Reported 2004
Negated 0
Speculated 0
Reported most in Abstract
Documents 1
Total Number 1
Disease Relevance 0.17
Pain Relevance 0.58

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

cytosol (DES) endoplasmic reticulum (BDKRB1) cytoskeleton (DES)
intracellular (DES) plasma membrane (BDKRB1) cytoskeleton organization (DES)
BDKRB1 (Homo sapiens)
DES (Homo sapiens)
Pain Link Frequency Relevance Heat
B1 receptor 9 100.00 Very High Very High Very High
bradykinin 1 100.00 Very High Very High Very High
antagonist 4 97.86 Very High Very High Very High
IPN 1 87.28 High High
Inflammation 2 86.40 High High
agonist 1 39.76 Quite Low
Pain 1 25.00 Low Low
Disease Link Frequency Relevance Heat
Inflammatory Pain 1 87.28 High High
INFLAMMATION 2 86.40 High High
Pain 1 5.00 Very Low Very Low Very Low
Sepsis 1 5.00 Very Low Very Low Very Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
Compound 11 (2-[(2R)-1-[(3,4-dichlorophenyl) sulfonyl]-3-oxo-1,2,3,4-tetrahydroquinoxalin-2-yl]-N-[2-[4-(4,5-dihydro-1H-imidazol-2-yl)phenyl]ethyl]acetamide) is a high-affinity nonpeptide antagonist for the human B1R, but it is potent at the rabbit B1R as well: its Ki value for the inhibition of [3H]Lys-des-Arg9-BK (bradykinin) binding to a novel myc-labeled rabbit B1R expressed in COS-1 is 22 pM.
B1R Binding (binding) of des-Arg9-BK associated with b1 receptor, antagonist and bradykinin
1) Confidence 0.05 Published 2004 Journal J. Pharmacol. Exp. Ther. Section Abstract Doc Link 15277582 Disease Relevance 0.17 Pain Relevance 0.58

General Comments

This test has worked.

Personal tools
Namespaces

Variants
Actions
Navigation
Toolbox