INT120477

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Context Info
Confidence 0.06
First Reported 2004
Last Reported 2008
Negated 0
Speculated 0
Reported most in Body
Documents 2
Total Number 3
Disease Relevance 1.07
Pain Relevance 0.69

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

Sugt1 (Rattus norvegicus)
Pain Link Frequency Relevance Heat
Opioid 4 99.68 Very High Very High Very High
addiction 2 96.60 Very High Very High Very High
alcohol 6 85.92 High High
antagonist 4 75.00 Quite High
Nucleus accumbens 1 69.60 Quite High
Dopamine 6 65.80 Quite High
methadone 3 58.12 Quite High
Neurotransmitter 1 54.00 Quite High
opiate 3 46.72 Quite Low
cocaine 1 46.08 Quite Low
Disease Link Frequency Relevance Heat
Disease 146 99.68 Very High Very High Very High
Opiate Addiction 1 96.60 Very High Very High Very High
Alcohol Addiction 1 86.16 High High
Drug Dependence 1 75.00 Quite High
Hypokinesia 8 72.72 Quite High
Dyskinesias 2 38.08 Quite Low
Coronary Artery Disease 2 31.52 Quite Low
Cerebrovascular Disease 2 29.36 Quite Low
Recurrence 2 25.00 Low Low
Syndrome 4 7.64 Low Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
The D and I allele distributions in the PD and control groups also revealed no significant differences (p=0.6).
Gene_expression (distributions) of allele associated with disease
1) Confidence 0.06 Published 2008 Journal The Open Neurology Journal Section Body Doc Link PMC2627518 Disease Relevance 0.81 Pain Relevance 0
Under these conditions, only the I allele produced a 335 bp amplicon.
Gene_expression (produced) of allele
2) Confidence 0.06 Published 2008 Journal The Open Neurology Journal Section Body Doc Link PMC2627518 Disease Relevance 0 Pain Relevance 0
Phychiatr. 3 (1997) 251] showed that the 7 repeat allele of the DRD4 receptor is significantly overpresented in the opioid-dependent cohort and confers a relative risk of 2.46.
Gene_expression (overpresented) of allele associated with opioid
3) Confidence 0.01 Published 2004 Journal Med. Hypotheses Section Abstract Doc Link 15288384 Disease Relevance 0.26 Pain Relevance 0.69

General Comments

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