INT120519

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Context Info
Confidence 0.78
First Reported 2004
Last Reported 2010
Negated 1
Speculated 0
Reported most in Body
Documents 15
Total Number 15
Disease Relevance 17.03
Pain Relevance 1.51

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

nucleoplasm (XRCC1) nucleus (XRCC1) intracellular (XRCC1)
Anatomy Link Frequency
lymph node 1
nephron 1
germline 1
cell component 1
XRCC1 (Homo sapiens)
Pain Link Frequency Relevance Heat
Pain 45 98.96 Very High Very High Very High
imagery 27 97.92 Very High Very High Very High
backache 2 97.20 Very High Very High Very High
Central nervous system 9 90.56 High High
Analgesic 8 87.60 High High
Paracetamol 6 84.24 Quite High
aspirin 2 80.56 Quite High
ischemia 2 77.92 Quite High
alcohol 7 76.56 Quite High
pain flank 2 76.56 Quite High
Disease Link Frequency Relevance Heat
Renal Cancer 752 100.00 Very High Very High Very High
Disease 209 100.00 Very High Very High Very High
Recurrence 26 99.78 Very High Very High Very High
Cancer 480 99.44 Very High Very High Very High
Hemangioma 1 99.36 Very High Very High Very High
Metastasis 298 98.98 Very High Very High Very High
Pain 41 98.96 Very High Very High Very High
Hemangioblastoma 2 98.68 Very High Very High Very High
Disease Progression 13 98.08 Very High Very High Very High
Solid Tumor 8 97.82 Very High Very High Very High

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
We report a case of a young man who developed an aggressive Xp11 translocation RCC.
Localization (translocation) of RCC associated with renal cancer
1) Confidence 0.78 Published 2009 Journal Int. J. Urol. Section Abstract Doc Link 19298350 Disease Relevance 0.96 Pain Relevance 0.10
On the basis of these findings, the case was diagnosed as Xp11 translocation RCC.
Localization (translocation) of RCC associated with renal cancer
2) Confidence 0.78 Published 2009 Journal Int. J. Urol. Section Abstract Doc Link 19298350 Disease Relevance 1.03 Pain Relevance 0.08
The fact that several patients who reported localized RCC also indicated continued pain is suggestive of disease progression.
Localization (localized) of RCC associated with pain, renal cancer and disease progression
3) Confidence 0.70 Published 2007 Journal Health Qual Life Outcomes Section Body Doc Link PMC1929060 Disease Relevance 1.83 Pain Relevance 0.23
Reflecting its higher prevalence, the total cost associated with localized RCC accounted for the greatest share (78.2%), followed by regional, distant, and unstaged RCC, at 18.3%, 2.8%, and 0.7%, respectively.
Localization (localized) of RCC
4) Confidence 0.58 Published 2007 Journal Urol. Oncol. Section Body Doc Link 17826652 Disease Relevance 0.06 Pain Relevance 0
Radical cancer surgery remains the only curative treatment in localized and advanced RCC.
Localization (localized) of RCC associated with cancer and renal cancer
5) Confidence 0.57 Published 2004 Journal World J Urol Section Abstract Doc Link 15290202 Disease Relevance 1.12 Pain Relevance 0.19
Most

of the cases of RCC are sporadic; however there are some defined types of RCC

Localization (cases) of RCC associated with renal cancer
6) Confidence 0.43 Published 2008 Journal Advances in Urology Section Body Doc Link PMC2581742 Disease Relevance 1.44 Pain Relevance 0.50
of RCC, reported by different authors.
Localization (reported) of RCC associated with renal cancer
7) Confidence 0.43 Published 2008 Journal Advances in Urology Section Body Doc Link PMC2581742 Disease Relevance 1.49 Pain Relevance 0.13
The greatest risk of recurrence following resection of RCC is within the first 3–5 years [4].
Localization (resection) of RCC associated with renal cancer and recurrence
8) Confidence 0.19 Published 2009 Journal Mol Cancer Section Body Doc Link PMC2667482 Disease Relevance 1.61 Pain Relevance 0.16
or clear cell RCC, who have no detectable VHL disease-causing germline mutation; somatic mosaicism for a VHL gene mutation still needs to be considered in
Localization (disease) of RCC in germline associated with disease
9) Confidence 0.11 Published 2008 Journal Advances in Urology Section Body Doc Link PMC2581790 Disease Relevance 1.12 Pain Relevance 0
Eligibility criteria for this study included no prior systemic treatment for RCC, confirmed metastatic RCC with a clear cell component, KPS ?
Neg (no) Localization (confirmed) of RCC in cell component associated with renal cancer
10) Confidence 0.07 Published 2008 Journal Biologics : Targets & Therapy Section Body Doc Link PMC2721410 Disease Relevance 1.17 Pain Relevance 0.05
Traditionally, surgical resection of RCC was ultimately the only consistent curative option for patients with localized disease, but the efficacy of available treatments for widespread disease remained marginal at best.
Localization (resection) of RCC associated with renal cancer and disease
11) Confidence 0.06 Published 2008 Journal J Hematol Oncol Section Body Doc Link PMC2527326 Disease Relevance 1.20 Pain Relevance 0.03
Renal cell carcinoma (RCC) accounts for 2% to 3% of all solid tumors in adults, and over 50,000 new cases were diagnosed in the United States in 2009.1 The primary treatment of localized RCC involves surgical resection or local nonsurgical ablative techniques.
Localization (localized) of RCC associated with renal cancer and solid tumor
12) Confidence 0.03 Published 2010 Journal Cancer management and research Section Body Doc Link PMC3004565 Disease Relevance 0.77 Pain Relevance 0
The following factors predict the risk of metastasis following radical nephrectomy (RN) for clinically localized RCC viz: size and stage of primary tumor, extent of regional lymph node involvement, if any, tumor histology, presence or absence of necrosis, and presence or absence of vascular invasion.
Localization (localized) of RCC in lymph node associated with necrosis, cancer, renal cancer and metastasis
13) Confidence 0.02 Published 2010 Journal Indian Journal of Urology : IJU : Journal of the Urological Society of India Section Body Doc Link PMC2938537 Disease Relevance 1.60 Pain Relevance 0
While the primary intent of LND in localized RCC is to increase the detection of nodal micrometastases thereby improving staging accuracy, in N + M0 disease, the principal goal is complete disease resection and cure.
Localization (localized) of RCC associated with renal cancer and disease
14) Confidence 0.02 Published 2010 Journal Indian Journal of Urology : IJU : Journal of the Urological Society of India Section Body Doc Link PMC2938537 Disease Relevance 0.95 Pain Relevance 0
Whereas the management of localized renal cell carcinoma (RCC) has evolved toward minimally invasive and nephron-sparing surgery, the treatment of endophytic renal tumors has remained problematic.
Localization (localized) of RCC in nephron associated with renal cancer
15) Confidence 0.01 Published 2010 Journal Korean Journal of Urology Section Body Doc Link PMC2924554 Disease Relevance 0.68 Pain Relevance 0.04

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