INT120526

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Context Info
Confidence 0.34
First Reported 2004
Last Reported 2010
Negated 1
Speculated 0
Reported most in Body
Documents 2
Total Number 2
Disease Relevance 0.65
Pain Relevance 0.18

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

small molecule metabolic process (SLCO1B3) plasma membrane (SLCO1B3) transmembrane transport (SLCO1B3)
cytoplasm (SLCO1B3)
Anatomy Link Frequency
hepatocytes 2
SLCO1B3 (Homo sapiens)
Pain Link Frequency Relevance Heat
Bile 17 98.64 Very High Very High Very High
imagery 90 72.20 Quite High
Opioid 1 50.00 Quite Low
fibrosis 7 5.00 Very Low Very Low Very Low
Pain 3 5.00 Very Low Very Low Very Low
headache 2 5.00 Very Low Very Low Very Low
agonist 1 5.00 Very Low Very Low Very Low
cva 1 5.00 Very Low Very Low Very Low
alcohol 1 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
Hepatocellular Cancer 32 91.36 High High
Cancer 24 79.44 Quite High
Hemangioma 11 70.96 Quite High
Metastasis 26 32.00 Quite Low
Cirrhosis 11 5.00 Very Low Very Low Very Low
Focal Nodular Hyperplasia 10 5.00 Very Low Very Low Very Low
Adenoma 8 5.00 Very Low Very Low Very Low
Liver Cancer 8 5.00 Very Low Very Low Very Low
Hypersensitivity 7 5.00 Very Low Very Low Very Low
Hepatitis C Virus Infection 5 5.00 Very Low Very Low Very Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
OATP1B3 expression was constant in SC human hepatocytes.
Positive_regulation (constant) of Gene_expression (expression) of OATP1B3 in hepatocytes
1) Confidence 0.34 Published 2004 Journal Pharm. Res. Section Body Doc Link 15290872 Disease Relevance 0 Pain Relevance 0
HCCs with gadoxetic acid uptake overexpressed OATP1B3 compared with HCCs without gadoxetic acid uptake, and OATP1B3 levels were significantly correlated with ERs (r = 0.91, P < 0.0001).
Positive_regulation (overexpressed) of Neg (without) Gene_expression (overexpressed) of OATP1B3
2) Confidence 0.17 Published 2010 Journal Biologics : Targets & Therapy Section Body Doc Link PMC2921257 Disease Relevance 0.65 Pain Relevance 0.18

General Comments

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