INT120569

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Context Info
Confidence 0.40
First Reported 2004
Last Reported 2004
Negated 0
Speculated 0
Reported most in Abstract
Documents 1
Total Number 1
Disease Relevance 1.22
Pain Relevance 0.06

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

intracellular (Egfr, Pik3r1) cytoplasm (Egfr, Pik3r1) signal transduction (Egfr, Pik3r1)
plasma membrane (Egfr, Pik3r1) nucleus (Egfr, Pik3r1) kinase activity (Egfr, Pik3r1)
Egfr (Mus musculus)
Pik3r1 (Mus musculus)
Pain Link Frequency Relevance Heat
cINOD 1 55.68 Quite High
COX2 1 25.00 Low Low
Disease Link Frequency Relevance Heat
Cancer 10 99.58 Very High Very High Very High
Adenoma 3 87.40 High High
Colon Cancer 3 81.56 Quite High
Malignant Neoplastic Disease 1 78.96 Quite High
Recurrence 1 5.00 Very Low Very Low Very Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
Tumors exhibited increased association of Egfr with clathrin heavy chain (CHC), Gab1, and p85alpha, the regulatory subunit of phosphoinositide 3-kinase (PI3K), and tumors also overexpressed c-Src, PDK1, and Akt.
Egfr Binding (association) of p85alpha associated with cancer
1) Confidence 0.40 Published 2004 Journal J. Biol. Chem. Section Abstract Doc Link 15294912 Disease Relevance 1.22 Pain Relevance 0.06

General Comments

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