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Context Info
Confidence 0.39
First Reported 2004
Last Reported 2010
Negated 0
Speculated 0
Reported most in Body
Documents 3
Total Number 3
Disease Relevance 0.48
Pain Relevance 0.25

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

plasma membrane (Chrna9)
Anatomy Link Frequency
neuron 1
central nervous system 1
Chrna9 (Rattus norvegicus)
Pain Link Frequency Relevance Heat
agonist 36 99.96 Very High Very High Very High
Central nervous system 1 96.36 Very High Very High Very High
Antinociceptive 1 91.92 High High
Root ganglion neuron 1 75.00 Quite High
Pyramidal cell 88 72.16 Quite High
imagery 4 45.84 Quite Low
qutenza 1 44.24 Quite Low
Kinase C 78 26.80 Quite Low
Pain 1 25.00 Low Low
tetrodotoxin 23 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
Nociception 4 97.64 Very High Very High Very High
Nash(non-alcoholic Steatohepatitis) 12 78.36 Quite High
Ganglion Cysts 1 75.00 Quite High
Cognitive Disorder 12 5.00 Very Low Very Low Very Low
Aging 3 5.00 Very Low Very Low Very Low
Brain Injury 3 5.00 Very Low Very Low Very Low
Disease 2 5.00 Very Low Very Low Very Low
Toxicity 1 5.00 Very Low Very Low Very Low
Schizophrenia 1 5.00 Very Low Very Low Very Low
Dementia 1 5.00 Very Low Very Low Very Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
In the present study, we focused on the recently described alpha 10-nAChR subunit, and on alpha 4 and alpha 7 subunits, which are the most abundant subunits in the central nervous system.
Transcription (described) of nAChR in central nervous system associated with central nervous system
1) Confidence 0.39 Published 2004 Journal Auton Neurosci Section Abstract Doc Link 15296793 Disease Relevance 0.40 Pain Relevance 0.13
7* nAChR ion channel was sufficient for significant depolarization and even excitation of the entire TM neuron, high densities of expression of functional ?
Transcription (channel) of nAChR in neuron
2) Confidence 0.13 Published 2010 Journal PLoS ONE Section Body Doc Link PMC2980465 Disease Relevance 0 Pain Relevance 0.07
EC50 concentration of the mACh receptor agonist MCh (10 ?
Transcription (concentration) of mACh receptor associated with agonist
3) Confidence 0.01 Published 2007 Journal Journal of Neurochemistry Section Body Doc Link PMC2658029 Disease Relevance 0.08 Pain Relevance 0.05

General Comments

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