INT120664

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Context Info
Confidence 0.01
First Reported 2004
Last Reported 2007
Negated 0
Speculated 0
Reported most in Abstract
Documents 3
Total Number 4
Disease Relevance 7.43
Pain Relevance 1.08

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

cell proliferation (TACC2) Golgi apparatus (TACC2) nucleolus (TACC2)
cytoskeleton (TACC2) nucleus (TACC2) microtubule organizing center (TACC2)
TACC2 (Homo sapiens)
Pain Link Frequency Relevance Heat
Angina 2 99.84 Very High Very High Very High
rheumatoid arthritis 20 98.04 Very High Very High Very High
Osteoarthritis 2 88.08 High High
Arthritis 2 85.36 High High
spinal inflammation 2 84.24 Quite High
Disease Link Frequency Relevance Heat
Acute Coronary Syndrome 20 99.96 Very High Very High Very High
Cv General 3 Under Development 2 99.84 Very High Very High Very High
Myocardial Infarction 6 98.84 Very High Very High Very High
Syndrome 14 98.16 Very High Very High Very High
Rheumatoid Arthritis 20 98.04 Very High Very High Very High
Disease 6 97.28 Very High Very High Very High
Dermatomyositis 2 95.64 Very High Very High Very High
Polymyositis 2 95.00 High High
Polymyalgia Rheumatica 2 93.96 High High
Systemic Lupus Erythematosus 2 92.68 High High

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
The commercial enzyme-linked immunosorbent assay (ELISA) was used to detect anti-CCP antibodies, including anti-CCP2 (regular, second generation of CCP antigen) and anti-CCP3 (third generation of CCP antigen) in disease-related specimens and normal controls.
Positive_regulation (generation) of anti-CCP2 associated with disease
1) Confidence 0.01 Published 2007 Journal Clin Rev Allergy Immunol Section Abstract Doc Link 17426360 Disease Relevance 2.12 Pain Relevance 0.44
At the same time, anti-CCP3 (not anti-CCP2) was significantly increased in samples isolated from patients with CREST syndrome.
Positive_regulation (increased) of anti-CCP2 associated with syndrome
2) Confidence 0.01 Published 2007 Journal Clin Rev Allergy Immunol Section Abstract Doc Link 17426360 Disease Relevance 2.15 Pain Relevance 0.46
In addition, serum concentrations of anti-beta2GPI antibodies were also increased in ACS.
Positive_regulation (increased) of anti-beta2GPI associated with acute coronary syndrome
3) Confidence 0.00 Published 2004 Journal Lupus Section Abstract Doc Link 15303568 Disease Relevance 1.54 Pain Relevance 0.08
Regarding subclasses of ACS, anti-beta2GPI IgA antibodies were elevated in unstable angina (UA) and myocardial infarction with ST elevation (STEMI), but not in myocardial infarction without ST elevation (NSTEMI).
Positive_regulation (elevated) of anti-beta2GPI associated with acute coronary syndrome, angina and myocardial infarction
4) Confidence 0.00 Published 2004 Journal Lupus Section Abstract Doc Link 15303568 Disease Relevance 1.62 Pain Relevance 0.10

General Comments

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