INT120700

Context Info Confidence 0.15 First Reported 2004 Last Reported 2004 Negated 0 Speculated 0 Reported most in Title Documents 1 Total Number 1 Disease Relevance 0.29 Pain Relevance 0.10

extracellular space (PRSS1, ICAM1) peptidase activity (PRSS1) extracellular region (PRSS1) cell adhesion (ICAM1) plasma membrane (ICAM1)

Anatomy Link Frequency leukocyte 1 PRSS1 (Homo sapiens) ICAM1 (Homo sapiens)

Pain Link Frequency Relevance Heat anesthesia 1 99.70

Disease Link Frequency Relevance Heat Pancreatitis 3 98.28 Injury 1 93.20

Sentences Mentioned In

Key:

Protein

Mutation

Event

Anatomy

Negation

Speculation

Pain term

Disease term

Membrane-bound ICAM-1 is upregulated by trypsin and contributes to leukocyte migration in acute pancreatitis.

trypsin Positive_regulation (upregulated) of ICAM-1 in leukocyte associated with anesthesia and pancreatitis

1) Confidence 0.15 Published 2004 Journal Am. J. Physiol. Gastrointest. Liver Physiol. Section Title Doc Link 15308472 Disease Relevance 0.29 Pain Relevance 0.10

General Comments

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