INT120716

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Context Info
Confidence 0.05
First Reported 2004
Last Reported 2004
Negated 0
Speculated 0
Reported most in Abstract
Documents 1
Total Number 1
Disease Relevance 0.46
Pain Relevance 0.21

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

nucleus (AKT1, TEP1) cytoplasm (AKT1, TEP1) cell differentiation (AKT1)
nucleoplasm (AKT1) transport (AKT1) protein modification process (AKT1)
Anatomy Link Frequency
MKN-45 1
AKT1 (Homo sapiens)
TEP1 (Homo sapiens)
Pain Link Frequency Relevance Heat
COX-2 inhibitor 4 95.52 Very High Very High Very High
cINOD 1 55.56 Quite High
COX2 1 25.00 Low Low
Disease Link Frequency Relevance Heat
Stomach Cancer 5 96.64 Very High Very High Very High
INFLAMMATION 1 55.00 Quite High

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
In the gastric cancer cell line MKN-45 nimesulide caused a time- and dose-dependent reduction in cell numbers and significantly inhibited telomerase and Akt/PKB activity; the inhibition of telomerase activity was partly associated with the attenuation of Akt/PKB activity.
Akt/PKB Binding (associated) of telomerase in MKN-45 associated with stomach cancer
1) Confidence 0.05 Published 2004 Journal Dig. Dis. Sci. Section Abstract Doc Link 15309882 Disease Relevance 0.46 Pain Relevance 0.21

General Comments

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