INT120959

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Context Info
Confidence 0.03
First Reported 2004
Last Reported 2004
Negated 0
Speculated 0
Reported most in Abstract
Documents 1
Total Number 1
Disease Relevance 0.14
Pain Relevance 0.28

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

transport (CFTR) ATPase activity (CFTR) plasma membrane (CFTR)
enzyme binding (CFTR) protein complex (CFTR) transmembrane transport (CFTR)
CFTR (Homo sapiens)
Pain Link Frequency Relevance Heat
Potency 3 98.60 Very High Very High Very High
COX-2 inhibitor 1 75.00 Quite High
Inflammation 2 70.24 Quite High
Analgesic 1 68.08 Quite High
Arthritis 1 54.80 Quite High
COX2 1 25.00 Low Low
cOX1 1 25.00 Low Low
Disease Link Frequency Relevance Heat
INFLAMMATION 2 70.24 Quite High
Arthritis 2 66.56 Quite High

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
The variations at/around position-4 of the C-5 phenyl ring in conjunction with a CF3 and CHF2 groups at C-3 exhibited a high degree of potency and selectivity index (SI) for COX-2 inhibition.
Protein_catabolism (groups) of CF3 associated with potency
1) Confidence 0.03 Published 2004 Journal Org. Biomol. Chem. Section Abstract Doc Link 15326524 Disease Relevance 0.14 Pain Relevance 0.28

General Comments

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