INT120961

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Context Info
Confidence 0.26
First Reported 2004
Last Reported 2010
Negated 0
Speculated 0
Reported most in Abstract
Documents 3
Total Number 3
Disease Relevance 1.02
Pain Relevance 0.53

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

cytosol (Pik3cb) signal transduction (Pik3cb) cell adhesion (Pik3cb)
nucleus (Pik3cb) cytoplasm (Pik3cb)
Pik3cb (Rattus norvegicus)
Pain Link Frequency Relevance Heat
ischemia 47 78.96 Quite High
Opioid 6 77.52 Quite High
narcan 2 74.36 Quite High
bradykinin 2 51.84 Quite High
adenocard 7 50.00 Quite Low
tolerance 1 5.00 Very Low Very Low Very Low
Potency 1 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
Insulin Resistance 14 94.56 High High
Cv Unclassified Under Development 45 78.96 Quite High
Myocardial Infarction 8 5.00 Very Low Very Low Very Low
Injury 5 5.00 Very Low Very Low Very Low
Reperfusion Injury 3 5.00 Very Low Very Low Very Low
Coronary Artery Disease 2 5.00 Very Low Very Low Very Low
Death 2 5.00 Very Low Very Low Very Low
Infarction 1 5.00 Very Low Very Low Very Low
Coronary Heart Disease 1 5.00 Very Low Very Low Very Low
Stress 1 5.00 Very Low Very Low Very Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
We have previously demonstrated that pharmacologically induced phosphorylation of PI3K/Akt in the first few min of reperfusion after a sustained ischemic insult is cardioprotective [14].
Positive_regulation (induced) of Phosphorylation (phosphorylation) of PI3K
1) Confidence 0.26 Published 2010 Journal Basic Res Cardiol Section Body Doc Link PMC3012213 Disease Relevance 0.13 Pain Relevance 0.14
This impaired glucose transportation was also due to signaling defects that included an attenuated p85 regulatory subunit of phosphatidylinositol 3-kinase (PI3-kinase) and Akt serine phosphorylation.
Positive_regulation (attenuated) of Phosphorylation (phosphorylation) of phosphatidylinositol 3-kinase
2) Confidence 0.14 Published 2004 Journal Horm. Metab. Res. Section Abstract Doc Link 15326568 Disease Relevance 0.44 Pain Relevance 0.19
This impaired glucose transportation was also due to signaling defects that included an attenuated p85 regulatory subunit of phosphatidylinositol 3-kinase (PI3-kinase) and Akt serine phosphorylation.
Positive_regulation (attenuated) of Phosphorylation (phosphorylation) of PI3-kinase
3) Confidence 0.14 Published 2004 Journal Horm. Metab. Res. Section Abstract Doc Link 15326568 Disease Relevance 0.44 Pain Relevance 0.19

General Comments

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