INT121000

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Context Info
Confidence 0.13
First Reported 2004
Last Reported 2004
Negated 0
Speculated 0
Reported most in Abstract
Documents 1
Total Number 1
Disease Relevance 0.67
Pain Relevance 1.25

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

nuclear envelope (Nrm) signal transduction (PAG1) nucleus (Nrm)
plasma membrane (PAG1) intracellular (PAG1)
Anatomy Link Frequency
spinal cord 1
PAG1 (Homo sapiens)
Nrm (Rattus norvegicus)
Pain Link Frequency Relevance Heat
Raphe magnus 3 100.00 Very High Very High Very High
Spinal cord 2 99.64 Very High Very High Very High
cINOD 6 99.20 Very High Very High Very High
Central grey 1 96.04 Very High Very High Very High
Pain 2 94.12 High High
Analgesic 4 86.80 High High
aspirin 3 82.40 Quite High
tolerance 7 75.00 Quite High
Opioid 2 75.00 Quite High
tail-flick 1 73.60 Quite High
Disease Link Frequency Relevance Heat
Urological Neuroanatomy 7 100.00 Very High Very High Very High
Pain 2 94.12 High High
INFLAMMATION 1 88.44 High High
Opiate Addiction 2 25.00 Low Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
The NSAID dipyrone (metamizol) has been shown to engage opioidergic circuits at the PAG, the NRM and the spinal cord, but it is unknown whether this can be generalized to typical NSAIDs and to systemic administration.
PAG Binding (engage) of NRM in spinal cord associated with raphe magnus, cinod, urological neuroanatomy and spinal cord
1) Confidence 0.13 Published 2004 Journal Pain Section Abstract Doc Link 15327823 Disease Relevance 0.67 Pain Relevance 1.25

General Comments

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