INT121076

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Context Info
Confidence 0.26
First Reported 2004
Last Reported 2010
Negated 0
Speculated 0
Reported most in Abstract
Documents 8
Total Number 8
Disease Relevance 3.66
Pain Relevance 0.62

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

cytoskeletal protein binding (Fabp3) cytosol (Fabp3) mitochondrion (Fabp3)
cytoplasm (Fabp3)
Anatomy Link Frequency
chest 3
Fabp3 (Rattus norvegicus)
Pain Link Frequency Relevance Heat
Angina 15 98.36 Very High Very High Very High
Disease Link Frequency Relevance Heat
Myocardial Infarction 39 99.80 Very High Very High Very High
Angina 13 98.36 Very High Very High Very High
Heart Disease 2 86.12 High High
Acute Coronary Syndrome 5 82.68 Quite High
Emergencies 3 72.40 Quite High
Injury 1 69.96 Quite High
Necrosis 1 50.00 Quite Low
Cv General 3 Under Development 2 5.00 Very Low Very Low Very Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
H-FABP sensitivity was 60% (89 out of 148 patients), significantly higher than troponin T [19% (28 out of 148 patients); P<0,05].
Regulation (sensitivity) of H-FABP
1) Confidence 0.26 Published 2008 Journal Eur J Emerg Med Section Body Doc Link 18460953 Disease Relevance 0.17 Pain Relevance 0
In the superacute phase of AMI within 3 hours, the diagnostic sensitivity of H-FABP was 93.1%, which was the highest of the four markers compared here.
Regulation (sensitivity) of H-FABP associated with myocardial infarction
2) Confidence 0.25 Published 2006 Journal J Immunoassay Immunochem Section Abstract Doc Link 16827225 Disease Relevance 0.75 Pain Relevance 0.09
H-FABP was measured by using 2 immunoassays, the H-FABP enzyme-linked immunosorbent assay (ELISA; Biocheck, Foster City, CA) and the H-FABP latex turbidimetric immunoassay (LTIA; HBI, Anyang, Korea).
Regulation (measured) of H-FABP
3) Confidence 0.19 Published 2010 Journal Am. J. Clin. Pathol. Section Abstract Doc Link 20551280 Disease Relevance 0.43 Pain Relevance 0
The results showed the cutoff value of H-FABP for AMI was 16.8 ng/ml, and its diagnostic sensitivity for AMI was 64.29% within 3 h and 84.38% within 6 h after onset of chest pain, and the diagnostic specificity for non-AMI was 100% within 3 h and 91.8% within 6 h.
Regulation (value) of H-FABP in chest associated with angina and myocardial infarction
4) Confidence 0.17 Published 2004 Journal J. Huazhong Univ. Sci. Technol. Med. Sci. Section Abstract Doc Link 15641689 Disease Relevance 1.07 Pain Relevance 0.18
To evaluate the diagnostic value of H-FABP for AMI in the early stage, the plasma levels of H-FABP were measured by sandwich ELISA in 93 patients with suspected AMI at admission within 6 h after onset of chest pain and 69 normal healthy subjects.
Regulation (value) of H-FABP in chest associated with angina and myocardial infarction
5) Confidence 0.17 Published 2004 Journal J. Huazhong Univ. Sci. Technol. Med. Sci. Section Abstract Doc Link 15641689 Disease Relevance 0.69 Pain Relevance 0.09
In patients presenting <4 h of symptom onset, sensitivity of H-FABP for MI was significantly higher than admission cTnT (73 vs. 55%; P = 0.043).
Regulation (sensitivity) of H-FABP
6) Confidence 0.12 Published 2008 Journal Eur. Heart J. Section Body Doc Link 18682444 Disease Relevance 0.14 Pain Relevance 0
CK-MB and TnT had higher specificities (73-100%) but significantly lower positive rates (22-27%) than the others (61-68%), resulting in greater sensitivities of H-FABP and myoglobin (75-80%) than those of CK-MB and TnT (29-35%).
Regulation (sensitivities) of H-FABP
7) Confidence 0.12 Published 2006 Journal Circ. J. Section Body Doc Link 16565558 Disease Relevance 0.21 Pain Relevance 0
Diagnostic value of heart fatty acid binding protein and myoglobin in patients admitted with chest pain.
Regulation (value) of heart fatty acid binding protein in chest associated with angina
8) Confidence 0.06 Published 2004 Journal Ann. Clin. Biochem. Section Title Doc Link 15333191 Disease Relevance 0.20 Pain Relevance 0.26

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