INT121096

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Context Info
Confidence 0.37
First Reported 2004
Last Reported 2009
Negated 0
Speculated 0
Reported most in Abstract
Documents 3
Total Number 3
Disease Relevance 1.23
Pain Relevance 1.29

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

aging (Calca) intracellular (Calca) lipid metabolic process (Trpv1)
cytoplasm (Calca) cytosol (Trpv1) extracellular space (Calca)
Anatomy Link Frequency
neurons 2
nerve 1
Calca (Rattus norvegicus)
Trpv1 (Rattus norvegicus)
Pain Link Frequency Relevance Heat
substance P 7 100.00 Very High Very High Very High
Calcitonin gene-related peptide 6 100.00 Very High Very High Very High
trigeminal ganglion 9 97.60 Very High Very High Very High
Neurotransmitter 1 92.36 High High
intrathecal 27 89.84 High High
dorsal root ganglion 25 80.84 Quite High
Spinal cord 23 71.84 Quite High
Dorsal horn 14 68.24 Quite High
unmyelinated 4 68.00 Quite High
Inflammation 17 56.56 Quite High
Disease Link Frequency Relevance Heat
Ganglion Cysts 35 97.60 Very High Very High Very High
Death 4 76.28 Quite High
INFLAMMATION 17 56.56 Quite High
Hypersensitivity 11 37.12 Quite Low
Pain 10 5.00 Very Low Very Low Very Low
Nociception 8 5.00 Very Low Very Low Very Low
Hyperalgesia 5 5.00 Very Low Very Low Very Low
Depression 4 5.00 Very Low Very Low Very Low
Bone Cancer 3 5.00 Very Low Very Low Very Low
Respiratory Failure 2 5.00 Very Low Very Low Very Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
In addition, we studied the colocalization of TRPV1-positive neurons with substance P (SP) and calcitonin gene-related peptide (CGRP) via confocal microscopy.
calcitonin gene-related peptide Binding (colocalization) of TRPV1 in neurons associated with calcitonin gene-related peptide and substance p
1) Confidence 0.37 Published 2004 Journal J. Comp. Neurol. Section Abstract Doc Link 15334649 Disease Relevance 0.28 Pain Relevance 0.38
In addition, we studied the colocalization of TRPV1-positive neurons with substance P (SP) and calcitonin gene-related peptide (CGRP) via confocal microscopy.
CGRP Binding (colocalization) of TRPV1 in neurons associated with calcitonin gene-related peptide and substance p
2) Confidence 0.37 Published 2004 Journal J. Comp. Neurol. Section Abstract Doc Link 15334649 Disease Relevance 0.28 Pain Relevance 0.38
Consistent with the loss of TRPV1 expressing central nerve terminals, the immunoreactivity of CGRP and SP associated with TRPV1 immunoreactivity was also significantly reduced (p<0.001) (Fig. 6E, F).
CGRP Binding (associated) of TRPV1 in nerve
3) Confidence 0.14 Published 2009 Journal PLoS ONE Section Body Doc Link PMC2737142 Disease Relevance 0.66 Pain Relevance 0.54

General Comments

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