INT121113

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Context Info
Confidence 0.65
First Reported 2004
Last Reported 2009
Negated 0
Speculated 0
Reported most in Body
Documents 2
Total Number 2
Disease Relevance 0.37
Pain Relevance 0.44

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

mitochondrion (Cyp11a1)
Anatomy Link Frequency
spinal 1
vesicles 1
Cyp11a1 (Rattus norvegicus)
Pain Link Frequency Relevance Heat
Neuropathic pain 4 98.20 Very High Very High Very High
Sciatic nerve 1 76.00 Quite High
Pain 4 69.28 Quite High
Neurotransmitter 1 53.68 Quite High
anesthesia 1 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
Neuropathic Pain 4 98.20 Very High Very High Very High
Pain 3 69.28 Quite High
Smith-lemli-opitz Syndrome 6 5.00 Very Low Very Low Very Low
Skin Cancer 6 5.00 Very Low Very Low Very Low
Malignant Neoplastic Disease 2 5.00 Very Low Very Low Very Low
Cancer 1 5.00 Very Low Very Low Very Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
This study combined cellular, molecular and biochemical approaches to investigate the gene expression and enzymatic activity of cytochrome P450side-chain-cleavage (P450scc) in spinal neural networks under normal and neuropathic pain states.
Protein_catabolism (cleavage) of P450scc in spinal associated with neuropathic pain
1) Confidence 0.65 Published 2004 Journal Cell. Mol. Life Sci. Section Abstract Doc Link 15338057 Disease Relevance 0.37 Pain Relevance 0.44
The side chain cleavage activity of P450scc in phospholipid vesicles was determined using [4-14C]cholesterol as substrate.
Protein_catabolism (cleavage) of P450scc in vesicles
2) Confidence 0.39 Published 2009 Journal PLoS ONE Section Body Doc Link PMC2629546 Disease Relevance 0 Pain Relevance 0

General Comments

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