INT121181

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Context Info
Confidence 0.06
First Reported 2004
Last Reported 2004
Negated 0
Speculated 0
Reported most in Abstract
Documents 1
Total Number 2
Disease Relevance 0.91
Pain Relevance 0

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

protein complex (Htt, Rest) cytoplasm (Htt, Rest) cytosol (Htt, Rest)
nucleus (Htt, Rest) cytoplasmic membrane-bounded vesicle (Htt, Bdnf) transcription factor binding (Htt, Rest)
Anatomy Link Frequency
Brain 4
Htt (Mus musculus)
Rest (Mus musculus)
Bdnf (Mus musculus)
Pain Link Frequency Relevance Heat
Dopamine 2 38.64 Quite Low
projection neuron 4 34.24 Quite Low
Enkephalin 4 25.00 Low Low
Disease Link Frequency Relevance Heat
Disease 12 99.48 Very High Very High Very High
Targeted Disruption 4 77.20 Quite High

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
Brain-derived neurotrophic factor (BDNF) protects striatal neurons and is regulated by Huntingtin through the interaction with the neuron-restrictive silencer factor.
Huntingtin Binding (interaction) of neuron-restrictive silencer factor in Brain Regulation (regulated) of Brain-derived neurotrophic factor
1) Confidence 0.06 Published 2004 Journal J. Neurosci. Section Abstract Doc Link 15342740 Disease Relevance 0.46 Pain Relevance 0
Brain-derived neurotrophic factor (BDNF) protects striatal neurons and is regulated by Huntingtin through the interaction with the neuron-restrictive silencer factor.
Huntingtin Binding (interaction) of neuron-restrictive silencer factor in Brain Regulation (regulated) of BDNF
2) Confidence 0.06 Published 2004 Journal J. Neurosci. Section Abstract Doc Link 15342740 Disease Relevance 0.46 Pain Relevance 0

General Comments

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