INT121216

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Context Info
Confidence 0.02
First Reported 2004
Last Reported 2004
Negated 0
Speculated 0
Reported most in Abstract
Documents 1
Total Number 1
Disease Relevance 0.32
Pain Relevance 2.02

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

cytoplasm (Prkca, Oprd1) plasma membrane (Prkca, Oprd1) mitochondrion (Prkca)
endoplasmic reticulum (Prkca) enzyme binding (Prkca) protein complex (Prkca)
Prkca (Mus musculus)
Oprd1 (Rattus norvegicus)
Pain Link Frequency Relevance Heat
Kinase C 7 100.00 Very High Very High Very High
opioid receptor 4 100.00 Very High Very High Very High
tolerance 11 99.60 Very High Very High Very High
Opioid 9 99.40 Very High Very High Very High
Morphine 3 95.64 Very High Very High Very High
nMDA receptor antagonist 1 93.92 High High
Pain 1 92.16 High High
nMDA receptor 2 89.24 High High
Glutamate receptor 1 82.92 Quite High
Neurotransmitter 1 81.52 Quite High
Disease Link Frequency Relevance Heat
Pain 2 92.16 High High
Targeted Disruption 2 89.84 High High

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
In the NMDA-mediated intracellular mechanisms of opioid tolerance, protein kinase C (PKC) modulates beta-opioid receptor activation.
PKC Regulation (modulates) of Positive_regulation (activation) of opioid receptor associated with kinase c, tolerance, opioid receptor and opioid
1) Confidence 0.02 Published 2004 Journal Acta anaesthesiologica Taiwanica : official journal of the Taiwan Society of Anesthesiologists Section Abstract Doc Link 15346705 Disease Relevance 0.32 Pain Relevance 2.02

General Comments

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