INT121308

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Context Info
Confidence 0.50
First Reported 2004
Last Reported 2008
Negated 0
Speculated 0
Reported most in Body
Documents 3
Total Number 4
Disease Relevance 0.60
Pain Relevance 0

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

nucleus (Xrcc1) intracellular (Xrcc1)
Xrcc1 (Mus musculus)
Pain Link Frequency Relevance Heat
palliative 1 50.00 Quite Low
Kinase C 5 5.00 Very Low Very Low Very Low
cytokine 2 5.00 Very Low Very Low Very Low
bDMF 2 5.00 Very Low Very Low Very Low
anesthesia 2 5.00 Very Low Very Low Very Low
adenocard 2 5.00 Very Low Very Low Very Low
cINOD 1 5.00 Very Low Very Low Very Low
Taxol 1 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
Infection 8 98.04 Very High Very High Very High
Hypoxia 3 85.16 High High
Reprotox - General 1 40 79.44 Quite High
Adhesions 2 58.72 Quite High
Hypersensitivity 6 58.24 Quite High
Prostate Cancer 1 50.00 Quite Low
Apoptosis 57 45.44 Quite Low
Cancer 21 42.88 Quite Low
Hyperplasia 5 41.68 Quite Low
Metastasis 6 31.48 Quite Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
Figure 1B shows the expression of XRCC1 protein in the control (scramble) and XRCC1-knockdown (XKD) shRNA replicating cells.
Positive_regulation (shows) of Gene_expression (expression) of XRCC1
1) Confidence 0.50 Published 2008 Journal Nucleic Acids Research Section Body Doc Link PMC2528184 Disease Relevance 0.15 Pain Relevance 0
Figure 1B shows the expression of XRCC1 protein in the control (scramble) and XRCC1-knockdown (XKD) shRNA replicating cells.
Positive_regulation (shows) of Gene_expression (expression) of XRCC1
2) Confidence 0.50 Published 2008 Journal Nucleic Acids Research Section Body Doc Link PMC2528184 Disease Relevance 0.16 Pain Relevance 0
Irradiation during this refractory period does not increase the expression of XRCC1 or ERCC1.
Positive_regulation (increase) of Gene_expression (expression) of XRCC1
3) Confidence 0.45 Published 2004 Journal Clin. Cancer Res. Section Body Doc Link 15355899 Disease Relevance 0.07 Pain Relevance 0
Radiation exposed DU145 cells had increased production of DNA repair proteins, XRCC1 and ERCC1 by ERK related mechanisms [42].
Positive_regulation (increased) of Gene_expression (production) of XRCC1
4) Confidence 0.16 Published 2004 Journal Cell Commun Signal Section Body Doc Link PMC449737 Disease Relevance 0.22 Pain Relevance 0

General Comments

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