INT121335

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Context Info
Confidence 0.68
First Reported 2004
Last Reported 2010
Negated 0
Speculated 0
Reported most in Body
Documents 10
Total Number 10
Disease Relevance 6.81
Pain Relevance 1.51

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

oxidoreductase activity (SCD) endoplasmic reticulum (SCD)
Anatomy Link Frequency
eye 1
medial 1
SCD (Homo sapiens)
Pain Link Frequency Relevance Heat
Delta-9-tetrahydrocannabinol 4 100.00 Very High Very High Very High
Catecholamine 7 99.98 Very High Very High Very High
Endogenous opioid 2 99.96 Very High Very High Very High
Cannabinoid 8 99.82 Very High Very High Very High
Endocannabinoid 2 99.04 Very High Very High Very High
Antinociceptive 2 98.76 Very High Very High Very High
Opioid 7 97.80 Very High Very High Very High
Pain 28 84.40 Quite High
guanethidine 1 84.04 Quite High
cva 3 75.08 Quite High
Disease Link Frequency Relevance Heat
Myocardial Infarction 101 100.00 Very High Very High Very High
Disease 59 100.00 Very High Very High Very High
Sickle Cell Anemia 52 100.00 Very High Very High Very High
Cardiovascular Disease 11 100.00 Very High Very High Very High
Hypertension 3 100.00 Very High Very High Very High
Pheochromocytoma 1 100.00 Very High Very High Very High
Heart Rate Under Development 10 99.92 Very High Very High Very High
Increased Venous Pressure Under Development 3 99.56 Very High Very High Very High
Fish-eye Disease 1 99.16 Very High Very High Very High
Toxicity 1 98.36 Very High Very High Very High

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
The diagnosis of haemoglobin type is simple and inexpensive and a comprehensive national screening programme to detect SCD in pregnant women and newborn babies was started in April 2002 as part of the Government's broader aims to tackle inequalities in health and community.
Localization (detect) of SCD associated with sickle cell anemia
1) Confidence 0.68 Published 2006 Journal Br J Nurs Section Abstract Doc Link 17167366 Disease Relevance 0.56 Pain Relevance 0.08
DISCUSSION: Efforts to improve home management of pain in SCD should incorporate programming designed to increase parent-child communication about pain and pain interference, confidence in disease management abilities, and improved knowledge of SCD and its care, particularly for families of older adolescents.


Localization (knowledge) of SCD
2) Confidence 0.64 Published 2008 Journal Clin J Pain Section Body Doc Link 18496309 Disease Relevance 0 Pain Relevance 0
DISCUSSION: Efforts to improve home management of pain in SCD should incorporate programming designed to increase parent-child communication about pain and pain interference, confidence in disease management abilities, and improved knowledge of SCD and its care, particularly for families of older adolescents.


Localization (knowledge) of SCD
3) Confidence 0.64 Published 2008 Journal Clin J Pain Section Body Doc Link 18496309 Disease Relevance 0 Pain Relevance 0
Those who had previously heard of SCD answered 34 items (94%) correctly (P<.05).
Localization (heard) of SCD associated with sickle cell anemia
4) Confidence 0.63 Published 2010 Journal Annals of Saudi Medicine Section Body Doc Link PMC2931779 Disease Relevance 0.40 Pain Relevance 0
A preliminary account of OF samples collected at the roadside showed the presence of amphetamine, cocaine, codeine, Delta-9-tetrahydrocannabinol, tramadol, and zopiclone.
Localization (presence) of Delta-9-tetrahydrocannabinol
5) Confidence 0.50 Published 2009 Journal Clin. Chem. Section Body Doc Link 19797719 Disease Relevance 0 Pain Relevance 0
The concomitant development of myocardiopathy and coronary vascular lesions or coronary and carotid artery intimal medial thickening by catecholamine toxicity is reflected by the frequent primary presentation of patients with catecholamine-secreting pheochromocytoma with cardiovascular disease, ie, hypertension arrhythmias, AMI, SCD, CHF, and vascular disease, which represents a clear example of the primary deleterious impact of catecholamines on the entire cardiovascular system causing adrenergic cardiovascular disease.
Localization (secreting) of SCD in medial associated with heart rate under development, cardiomyopathy, catecholamine, increased venous pressure under development, pheochromocytoma, toxicity, cardiovascular disease, hypertension and myocardial infarction
6) Confidence 0.45 Published 2004 Journal Am J Ther Section Abstract Doc Link 15356432 Disease Relevance 2.50 Pain Relevance 0.33
SCD was reported for almost all sports, the majority involved soccer (30%), basketball (25%) and runners (15%) [21].
Localization (reported) of SCD associated with myocardial infarction
7) Confidence 0.43 Published 2010 Journal Sports Med Arthrosc Rehabil Ther Technol Section Body Doc Link PMC2923123 Disease Relevance 1.36 Pain Relevance 0
Considering the importance of SCD in athletes and the requisite for an update of this matter, we endeavored to describe SCD in athletes.
Localization (importance) of SCD associated with myocardial infarction
8) Confidence 0.43 Published 2010 Journal Sports Med Arthrosc Rehabil Ther Technol Section Abstract Doc Link PMC2923123 Disease Relevance 0.82 Pain Relevance 0
SCD needs to be differentiated from other lipid keratopathies and particular from lethithin: cholesterol acyltransferase disease (LCAT disease, Norum disease) and fish eye disease caused by different mutations in the LCAT gene.


Localization (disease) of SCD in eye associated with fish-eye disease and disease
9) Confidence 0.05 Published 2009 Journal Orphanet J Rare Dis Section Body Doc Link PMC2695576 Disease Relevance 0.94 Pain Relevance 0
Cannabinoids such as Delta-9-tetrahydrocannabinol (THC) release endogenous opioids and endocannabinoids such as anandamide (AEA) also alter endogenous opioid tone.
Localization (release) of Delta-9-tetrahydrocannabinol associated with endocannabinoid, cannabinoid, endogenous opioid and delta-9-tetrahydrocannabinol
10) Confidence 0.05 Published 2009 Journal Int Rev Psychiatry Section Abstract Doc Link 19367508 Disease Relevance 0.23 Pain Relevance 1.09

General Comments

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