INT121362

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Context Info
Confidence 0.51
First Reported 2004
Last Reported 2004
Negated 0
Speculated 0
Reported most in Title
Documents 1
Total Number 2
Disease Relevance 0.17
Pain Relevance 1.12

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

cytosol (Trpv1) extracellular space (Ins1) extracellular region (Ins1)
plasma membrane (Trpv1) carbohydrate metabolic process (Ins1) cytoplasm (Ins1)
Anatomy Link Frequency
beta cells 4
Trpv1 (Rattus norvegicus)
Ins1 (Rattus norvegicus)
Pain Link Frequency Relevance Heat
Calcium channel 2 99.76 Very High Very High Very High
qutenza 14 99.60 Very High Very High Very High
Disease Link Frequency Relevance Heat
Hyperinsulinism 2 90.48 High High

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
We demonstrated for the first time that TRPV1 is functionally expressed in rat islet beta cells and plays a role in insulin secretion as a calcium channel.
TRPV1 Regulation (role) of Localization (secretion) of insulin in beta cells associated with calcium channel
1) Confidence 0.51 Published 2004 Journal Biochem. Biophys. Res. Commun. Section Abstract Doc Link 15358238 Disease Relevance 0.09 Pain Relevance 0.48
Transient receptor potential vanilloid subfamily 1 expressed in pancreatic islet beta cells modulates insulin secretion in rats.
vanilloid subfamily 1 Regulation (modulates) of Localization (secretion) of insulin in beta cells associated with qutenza
2) Confidence 0.31 Published 2004 Journal Biochem. Biophys. Res. Commun. Section Title Doc Link 15358238 Disease Relevance 0.08 Pain Relevance 0.64

General Comments

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