INT121374

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Context Info
Confidence 0.39
First Reported 2005
Last Reported 2006
Negated 1
Speculated 0
Reported most in Body
Documents 2
Total Number 2
Disease Relevance 1.01
Pain Relevance 0.29

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

isomerase activity (MIF) cell proliferation (MIF) extracellular space (MIF)
extracellular region (MIF) cytoplasm (MIF)
Anatomy Link Frequency
macrophage 1
bile 1
MIF (Homo sapiens)
Pain Link Frequency Relevance Heat
aspirin 5 100.00 Very High Very High Very High
Bile 5 100.00 Very High Very High Very High
Catecholamine 1 96.16 Very High Very High Very High
cINOD 1 75.00 Quite High
Inflammatory mediators 5 50.00 Quite Low
Inflammatory marker 4 41.88 Quite Low
anesthesia 4 6.32 Low Low
Inflammation 15 5.00 Very Low Very Low Very Low
cytokine 9 5.00 Very Low Very Low Very Low
Inflammatory response 7 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
Skin Cancer 9 99.84 Very High Very High Very High
Cancer 3 96.80 Very High Very High Very High
Multiple Organ Failure 13 89.32 High High
INFLAMMATION 30 50.00 Quite Low
Malignant Neoplastic Disease 1 43.84 Quite Low
Hematological Disease 3 24.16 Low Low
Injury 4 5.00 Very Low Very Low Very Low
Postoperative Complications 3 5.00 Very Low Very Low Very Low
Systemic Inflammatory Response Syndrome 2 5.00 Very Low Very Low Very Low
Sepsis 2 5.00 Very Low Very Low Very Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
The aim of this study was to determine the macrophage migration inhibitory factor (MIF) protein and mRNA expression in esophageal squamous cell carcinoma (ESCC), and the effect of bile acids, aspirin and a selective cyclooxygenase-2 (COX-2) inhibitor, NS398, on MIF expression in ESCC cells in vitro.
Regulation (effect) of in macrophage Gene_expression (expression) of MIF in bile associated with aspirin, bile and skin cancer
1) Confidence 0.39 Published 2005 Journal Carcinogenesis Section Abstract Doc Link 15358635 Disease Relevance 0.64 Pain Relevance 0.25
Notably, levels of MIF or IL-6 were not significantly different between patients who needed dobutamine or low doses of vasopressors, and those who required no catecholamine infusions.
Neg (not) Regulation (different) of Gene_expression (levels) of MIF associated with catecholamine
2) Confidence 0.17 Published 2006 Journal Crit Care Section Body Doc Link PMC1550915 Disease Relevance 0.37 Pain Relevance 0.05

General Comments

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