INT121387

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Context Info
Confidence 0.40
First Reported 2004
Last Reported 2010
Negated 1
Speculated 0
Reported most in Abstract
Documents 3
Total Number 3
Disease Relevance 2.60
Pain Relevance 0.25

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

cell proliferation (CD5) plasma membrane (CD5)
Anatomy Link Frequency
bone marrow 2
MALT 2
CD5 (Homo sapiens)
Pain Link Frequency Relevance Heat
Pain 2 88.52 High High
Crohn's disease 2 75.00 Quite High
Pain refractory 1 62.88 Quite High
nud 1 62.44 Quite High
tolerance 1 30.88 Quite Low
cytokine 5 18.04 Low Low
corticosteroid 1 5.00 Very Low Very Low Very Low
Inflammation 1 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
Mantle-cell Lymphoma 7 99.76 Very High Very High Very High
Cancer 7 98.74 Very High Very High Very High
Disease 5 96.04 Very High Very High Very High
Lymphatic System Cancer 14 95.64 Very High Very High Very High
Pain 1 88.52 High High
Toothache 1 88.12 High High
Pressure And Volume Under Development 1 86.80 High High
Acquired Immune Deficiency Syndrome Or Hiv Infection 5 86.44 High High
Adult T-cell Leukemia-lymphoma 11 82.80 Quite High
Immunodeficiency 1 73.60 Quite High

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
The lack of CD5 expression underscores the importance of performing thorough immunohistochemical studies, particularly to exclude MALT lymphoma.
Negative_regulation (lack) of Gene_expression (expression) of CD5 in MALT associated with lymphatic system cancer
1) Confidence 0.40 Published 2004 Journal Leuk. Lymphoma Section Abstract Doc Link 15359648 Disease Relevance 1.16 Pain Relevance 0.16
The tumour cells were immunopositivity for CD20 and CD10, expressed weak positivity for CD3, negative for CD5 and showed > 90% positivity for Ki-67.
Negative_regulation (positivity) of Neg (negative) Gene_expression (negative) of CD5 associated with cancer
2) Confidence 0.23 Published 2010 Journal Malays J Pathol Section Abstract Doc Link 20614728 Disease Relevance 1.07 Pain Relevance 0.09
Flow cytometry of the bone marrow biopsy revealed that the majority of cells were immunoreactive for CD45, CD2, CD3, CD4, and CD30, whereas the expression of CD5 and CD7 was greatly reduced compared to CD2 and CD3.
Negative_regulation (reduced) of Gene_expression (expression) of CD5 in bone marrow
3) Confidence 0.15 Published 2007 Journal J Gen Intern Med Section Body Doc Link PMC1824742 Disease Relevance 0.37 Pain Relevance 0

General Comments

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