INT121388

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Context Info
Confidence 0.28
First Reported 2004
Last Reported 2008
Negated 0
Speculated 0
Reported most in Abstract
Documents 2
Total Number 2
Disease Relevance 2.71
Pain Relevance 0.32

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

cell morphogenesis (BCL6) nucleolus (BCL6) nucleus (BCL6)
intracellular (BCL6)
BCL6 (Homo sapiens)
Pain Link Frequency Relevance Heat
medulla 1 83.68 Quite High
Angina 1 83.60 Quite High
Pain refractory 1 79.52 Quite High
nud 1 79.08 Quite High
Crohn's disease 2 76.76 Quite High
Disease Link Frequency Relevance Heat
Hodgkin's Disease 1 93.84 High High
Sclerosis 1 92.44 High High
Diffuse Large B-cell Lymphoma 2 91.84 High High
Cancer 2 87.32 High High
Mantle-cell Lymphoma 7 86.96 High High
Lymphatic System Cancer 10 86.36 High High
Cough 1 84.16 Quite High
Angina 1 83.60 Quite High
Dyspnea 1 82.64 Quite High
Superior Vena Cava Syndrome 1 81.60 Quite High

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
Immunohistochemichally, the cells were positive for CD20, CD79a, CD43 and cyclin D1, but negative for CD3, CD5 and bcl-6.
Positive_regulation (negative) of bcl-6
1) Confidence 0.28 Published 2004 Journal Leuk. Lymphoma Section Abstract Doc Link 15359648 Disease Relevance 1.41 Pain Relevance 0.19
Its main molecular characteristics include: gains in 9p segments, p53 mutations, BCL-2 and MAL gene over-expression, somatic mutations of IgVH genes, BCL-6, PIM-1, PAX-5, RhoH/TTF, and c-MYC, and constitutional NF-kappaB activation.
Positive_regulation (activation) of BCL-6
2) Confidence 0.02 Published 2008 Journal Crit. Rev. Oncol. Hematol. Section Abstract Doc Link 18774728 Disease Relevance 1.31 Pain Relevance 0.13

General Comments

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