INT12140

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Context Info
Confidence 0.44
First Reported 1992
Last Reported 1992
Negated 1
Speculated 0
Reported most in Abstract
Documents 1
Total Number 5
Disease Relevance 1.67
Pain Relevance 2.18

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

mitochondrion (Chat) signal transduction (Ngf) extracellular space (Ngf)
aging (Ngf) extracellular region (Ngf) transferase activity, transferring acyl groups (Chat)
Anatomy Link Frequency
neuron 4
Ngf (Rattus norvegicus)
Chat (Rattus norvegicus)
Pain Link Frequency Relevance Heat
tetrodotoxin 20 100.00 Very High Very High Very High
Nerve growth factor 20 100.00 Very High Very High Very High
GABAergic 5 94.96 High High
Disease Link Frequency Relevance Heat
Generalized Anxiety Disorder 20 100.00 Very High Very High Very High

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
We studied the effects of insulin, nerve growth factor (NGF), and tetrodotoxin (TTX) on cellular metabolism and the activity of glutamic acid decarboxylase (GAD) and choline acetyltransferase (ChAT) in neuron-rich cultures prepared from embryonic day 15 rat striatum.
nerve growth factor Regulation (effects) of ChAT in neuron associated with tetrodotoxin, nerve growth factor and generalized anxiety disorder
1) Confidence 0.44 Published 1992 Journal J. Neurochem. Section Abstract Doc Link 1629717 Disease Relevance 0.34 Pain Relevance 0.42
We studied the effects of insulin, nerve growth factor (NGF), and tetrodotoxin (TTX) on cellular metabolism and the activity of glutamic acid decarboxylase (GAD) and choline acetyltransferase (ChAT) in neuron-rich cultures prepared from embryonic day 15 rat striatum.
NGF Regulation (effects) of ChAT in neuron associated with tetrodotoxin, nerve growth factor and generalized anxiety disorder
2) Confidence 0.44 Published 1992 Journal J. Neurochem. Section Abstract Doc Link 1629717 Disease Relevance 0.34 Pain Relevance 0.42
We studied the effects of insulin, nerve growth factor (NGF), and tetrodotoxin (TTX) on cellular metabolism and the activity of glutamic acid decarboxylase (GAD) and choline acetyltransferase (ChAT) in neuron-rich cultures prepared from embryonic day 15 rat striatum.
nerve growth factor Regulation (effects) of choline acetyltransferase in neuron associated with tetrodotoxin, nerve growth factor and generalized anxiety disorder
3) Confidence 0.44 Published 1992 Journal J. Neurochem. Section Abstract Doc Link 1629717 Disease Relevance 0.34 Pain Relevance 0.42
We studied the effects of insulin, nerve growth factor (NGF), and tetrodotoxin (TTX) on cellular metabolism and the activity of glutamic acid decarboxylase (GAD) and choline acetyltransferase (ChAT) in neuron-rich cultures prepared from embryonic day 15 rat striatum.
NGF Regulation (effects) of choline acetyltransferase in neuron associated with tetrodotoxin, nerve growth factor and generalized anxiety disorder
4) Confidence 0.44 Published 1992 Journal J. Neurochem. Section Abstract Doc Link 1629717 Disease Relevance 0.34 Pain Relevance 0.42
NGF increased ChAT activity; TTX had no effect on ChAT activity.
NGF Neg (no) Regulation (effect) of ChAT associated with tetrodotoxin and nerve growth factor
5) Confidence 0.26 Published 1992 Journal J. Neurochem. Section Abstract Doc Link 1629717 Disease Relevance 0.29 Pain Relevance 0.50

General Comments

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