INT121453

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Context Info
Confidence 0.28
First Reported 2004
Last Reported 2004
Negated 0
Speculated 0
Reported most in Abstract
Documents 1
Total Number 1
Disease Relevance 0.42
Pain Relevance 0.60

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

plasma membrane (Bdkrb2, Trpv1) cytosol (Trpv1) endosome (Bdkrb2)
lipid metabolic process (Trpv1) signal transducer activity (Bdkrb2)
Bdkrb2 (Rattus norvegicus)
Trpv1 (Rattus norvegicus)
Pain Link Frequency Relevance Heat
b2 receptor 2 100.00 Very High Very High Very High
bradykinin 4 96.48 Very High Very High Very High
dorsal root ganglion 1 92.32 High High
Inflammation 1 86.16 High High
Pain 1 85.24 High High
Nerve growth factor 1 81.68 Quite High
Inflammatory mediators 1 79.92 Quite High
Hyperalgesia 1 76.20 Quite High
qutenza 1 25.00 Low Low
Disease Link Frequency Relevance Heat
Ganglion Cysts 1 92.32 High High
INFLAMMATION 2 86.16 High High
Pain 1 85.24 High High
Hyperalgesia 1 76.20 Quite High

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
The bradykinin B2 receptor then sensitizes vanilloid receptor 1 activity by facilitating non-selective Ca2+ channel activity, increasing the intracellular Ca2+ concentration from the extracellular pool.
bradykinin B2 receptor Positive_regulation (sensitizes) of vanilloid receptor 1 associated with b2 receptor
1) Confidence 0.28 Published 2004 Journal Eur. J. Pharmacol. Section Abstract Doc Link 15363973 Disease Relevance 0.42 Pain Relevance 0.60

General Comments

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