INT121543

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Context Info
Confidence 0.29
First Reported 2004
Last Reported 2008
Negated 0
Speculated 0
Reported most in Body
Documents 4
Total Number 8
Disease Relevance 1.63
Pain Relevance 2.21

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

peptidase activity (PCSK1) extracellular space (PCSK1) small molecule metabolic process (PCSK1)
Golgi apparatus (PCSK1) embryo development (PCSK1) cellular nitrogen compound metabolic process (PCSK1)
Anatomy Link Frequency
amygdala 10
PC-3 3
lateral 2
T24 1
PCSK1 (Homo sapiens)
Pain Link Frequency Relevance Heat
amygdala 225 100.00 Very High Very High Very High
sodium channel 1 82.56 Quite High
tetrodotoxin 1 75.52 Quite High
lidocaine 4 50.00 Quite Low
Hippocampus 35 32.32 Quite Low
Central grey 30 29.52 Quite Low
depression 35 5.00 Very Low Very Low Very Low
imagery 20 5.00 Very Low Very Low Very Low
ketamine 10 5.00 Very Low Very Low Very Low
anesthesia 10 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
Stress 150 93.64 High High
Reprotox - General 1 4 84.80 Quite High
Bladder Cancer 2 64.60 Quite High
Urological Neuroanatomy 30 29.52 Quite Low
Anxiety Disorder 105 5.00 Very Low Very Low Very Low
Depression 35 5.00 Very Low Very Low Very Low
Drug Dependence 5 5.00 Very Low Very Low Very Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
PC-3 and T24 cells were successfully transfected in the bladder.
Positive_regulation (transfected) of Gene_expression (transfected) of PC-3 in PC-3
1) Confidence 0.29 Published 2004 Journal J. Urol. Section Body Doc Link 15371873 Disease Relevance 0.06 Pain Relevance 0
We also found that individual differences in metabolic activity in this overlapping amygdala region assessed during NEC or ALN were positively correlated with individual differences in the screening measures of anxious temperament that were determined 4.3 months prior to the FDG studies (early temperament vs. later NEC amygdala activity, r(33)?
Positive_regulation (differences) of Gene_expression (assessed) of NEC in amygdala associated with amygdala
2) Confidence 0.14 Published 2008 Journal PLoS ONE Section Body Doc Link PMC2430534 Disease Relevance 0.25 Pain Relevance 0.40
We also found that individual differences in metabolic activity in this overlapping amygdala region assessed during NEC or ALN were positively correlated with individual differences in the screening measures of anxious temperament that were determined 4.3 months prior to the FDG studies (early temperament vs. later NEC amygdala activity, r(33)?
Positive_regulation (later) of Gene_expression (activity) of NEC in amygdala associated with amygdala
3) Confidence 0.14 Published 2008 Journal PLoS ONE Section Body Doc Link PMC2430534 Disease Relevance 0.22 Pain Relevance 0.43
We also found that individual differences in metabolic activity in this overlapping amygdala region assessed during NEC or ALN were positively correlated with individual differences in the screening measures of anxious temperament that were determined 4.3 months prior to the FDG studies (early temperament vs. later NEC amygdala activity, r(33)?
Positive_regulation (temperament) of Gene_expression (activity) of NEC in amygdala associated with amygdala
4) Confidence 0.14 Published 2008 Journal PLoS ONE Section Body Doc Link PMC2430534 Disease Relevance 0.22 Pain Relevance 0.43
We also found that individual differences in metabolic activity in this overlapping amygdala region assessed during NEC or ALN were positively correlated with individual differences in the screening measures of anxious temperament that were determined 4.3 months prior to the FDG studies (early temperament vs. later NEC amygdala activity, r(33)?
Positive_regulation (during) of Gene_expression (assessed) of NEC in amygdala associated with amygdala
5) Confidence 0.14 Published 2008 Journal PLoS ONE Section Body Doc Link PMC2430534 Disease Relevance 0.24 Pain Relevance 0.39
We also found that individual differences in metabolic activity in this overlapping amygdala region assessed during NEC or ALN were positively correlated with individual differences in the screening measures of anxious temperament that were determined 4.3 months prior to the FDG studies (early temperament vs. later NEC amygdala activity, r(33)?
Positive_regulation (during) of Gene_expression (activity) of NEC in amygdala associated with amygdala
6) Confidence 0.14 Published 2008 Journal PLoS ONE Section Body Doc Link PMC2430534 Disease Relevance 0.24 Pain Relevance 0.45
In comparison to the LNCaP cell line, Hes1, another downstream target, showed elevated expression in the metastatic PC-3 and PC-3M cells and promoted lateral motility.
Positive_regulation (elevated) of Gene_expression (expression) of PC-3 in lateral
7) Confidence 0.13 Published 2006 Journal Prostate Cancer Prostatic Dis. Section Abstract Doc Link 16832382 Disease Relevance 0.32 Pain Relevance 0.12
PC-3 and T24 cells were successfully transfected in the bladder.
Positive_regulation (transfected) of in T24 Gene_expression (transfected) of PC-3 in PC-3
8) Confidence 0.10 Published 2004 Journal J. Urol. Section Body Doc Link 15371873 Disease Relevance 0.06 Pain Relevance 0

General Comments

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