INT121581

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Context Info
Confidence 0.36
First Reported 2004
Last Reported 2004
Negated 0
Speculated 0
Reported most in Abstract
Documents 1
Total Number 1
Disease Relevance 0.59
Pain Relevance 0.24

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

cytosol (PIK3CG) signal transduction (GDF15) extracellular space (GDF15)
extracellular region (GDF15) plasma membrane (PIK3CG) cell-cell signaling (GDF15)
PIK3CG (Homo sapiens)
GDF15 (Homo sapiens)
Pain Link Frequency Relevance Heat
cINOD 3 84.28 Quite High
cytokine 1 25.00 Low Low
Disease Link Frequency Relevance Heat
Colon Cancer 1 97.36 Very High Very High Very High
Apoptosis 2 90.36 High High
INFLAMMATION 3 84.04 Quite High
Cancer 1 76.20 Quite High

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
PI3K inhibition by LY294002 showed an increase in NAG-1 protein and mRNA expression, and 1l-6-hydroxymethyl-chiro-inositol 2(R)-2-O-methyl-3-O-octadecylcarbonate (AKT inhibitor) also induced NAG-1 expression.
Negative_regulation (inhibition) of PI3K Positive_regulation (increase) of NAG-1
1) Confidence 0.36 Published 2004 Journal J. Biol. Chem. Section Abstract Doc Link 15377673 Disease Relevance 0.59 Pain Relevance 0.24

General Comments

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