INT121583

Context Info Confidence 0.11 First Reported 2004 Last Reported 2004 Negated 0 Speculated 0 Reported most in Abstract Documents 1 Total Number 1 Disease Relevance 0.49 Pain Relevance 0.20

cytosol (GSK3A) signal transduction (GDF15) extracellular space (GDF15) extracellular region (GDF15) carbohydrate metabolic process (GSK3A) cell-cell signaling (GDF15)

GSK3A (Homo sapiens) GDF15 (Homo sapiens)

Pain Link Frequency Relevance Heat cINOD 3 75.00 cytokine 1 25.00

Disease Link Frequency Relevance Heat Apoptosis 2 89.28 Colon Cancer 1 76.88 INFLAMMATION 3 75.00 Cancer 1 55.72

Sentences Mentioned In

Key:

Protein

Mutation

Event

Anatomy

Negation

Speculation

Pain term

Disease term

Furthermore, the down-regulation of GSK-3 gene using small interference RNA resulted in a decline of the NAG-1 expression in the presence of LY294002.

Negative_regulation (down-regulation) of GSK-3 gene Negative_regulation (decline) of Gene_expression (expression) of NAG-1

1) Confidence 0.11 Published 2004 Journal J. Biol. Chem. Section Abstract Doc Link 15377673 Disease Relevance 0.49 Pain Relevance 0.20

General Comments

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