INT121723

From wiki-pain
Jump to: navigation, search
Context Info
Confidence 0.44
First Reported 2004
Last Reported 2010
Negated 0
Speculated 1
Reported most in Body
Documents 1
Total Number 2
Disease Relevance 0.61
Pain Relevance 1.29

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

cytosol (Pik3cb) signal transduction (Pik3cb) cell adhesion (Pik3cb)
nucleus (Pik3cb) cytoplasm (Pik3cb)
Anatomy Link Frequency
neurons 2
Pik3cb (Rattus norvegicus)
Pain Link Frequency Relevance Heat
IPN 2 99.84 Very High Very High Very High
Inflammation 5 99.68 Very High Very High Very High
opioid receptor 131 95.04 Very High Very High Very High
nociceptor 1 94.84 High High
Hyperalgesia 5 89.96 High High
qutenza 7 88.60 High High
Stimulus evoked pain 1 87.16 High High
antagonist 37 73.48 Quite High
c fibre 1 59.84 Quite High
agonist 11 54.84 Quite High
Disease Link Frequency Relevance Heat
Inflammatory Pain 2 99.84 Very High Very High Very High
INFLAMMATION 2 99.68 Very High Very High Very High
Hyperalgesia 5 89.96 High High
Hypersensitivity 1 87.16 High High
Pain 12 86.48 High High
Irritable Bowel Syndrome /

Irritable Bowel Syndrome Super / Visceral Pain

15 40.48 Quite Low
Irritable Bowel Syndrome /

Irritable Bowel Syndrome Super

32 5.00 Very Low Very Low Very Low
Nociception 7 5.00 Very Low Very Low Very Low
Toxicity 1 5.00 Very Low Very Low Very Low
Disease 1 5.00 Very Low Very Low Very Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
We examined the activation of PI3K in primary sensory DRG neurons by these inflammatory agents and the contribution of PI3K activation to inflammatory pain.
Spec (examined) Regulation (contribution) of Spec (examined) Positive_regulation (activation) of PI3K in neurons associated with inflammation and ipn
1) Confidence 0.44 Published 2004 Journal J. Neurosci. Section Abstract Doc Link 15385613 Disease Relevance 0.61 Pain Relevance 0.90
These findings are consistent with the observation that activation and internalization of a GPCR can be regulated by activation of the PI3K/AKT pathway [43].
Regulation (regulated) of Positive_regulation (activation) of PI3K
2) Confidence 0.22 Published 2010 Journal Mol Pain Section Body Doc Link PMC2908066 Disease Relevance 0 Pain Relevance 0.39

General Comments

This test has worked.

Personal tools
Namespaces

Variants
Actions
Navigation
Toolbox