INT121763

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Context Info
Confidence 0.30
First Reported 2003
Last Reported 2008
Negated 0
Speculated 0
Reported most in Body
Documents 4
Total Number 4
Disease Relevance 2.39
Pain Relevance 0

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

ribosome (Rps6ka1) nucleus (Rps6ka1) kinase activity (Rps6ka1)
transcription factor binding (Rps6ka1) cytoplasm (Rps6ka1)
Anatomy Link Frequency
cortex 1
Rps6ka1 (Mus musculus)
Pain Link Frequency Relevance Heat
Action potential 1 49.68 Quite Low
tetrodotoxin 1 46.96 Quite Low
Bile 3 5.00 Very Low Very Low Very Low
palliative 2 5.00 Very Low Very Low Very Low
metalloproteinase 2 5.00 Very Low Very Low Very Low
imagery 2 5.00 Very Low Very Low Very Low
Chronic pancreatitis 1 5.00 Very Low Very Low Very Low
Inflammation 1 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
Death 14 98.88 Very High Very High Very High
Adenocarcinoma 60 96.80 Very High Very High Very High
Apoptosis 78 85.16 High High
Cancer 169 82.96 Quite High
Hepatocellular Cancer 72 50.00 Quite Low
Liver Cancer 24 35.36 Quite Low
Metastasis 9 28.08 Quite Low
Severe Combined Immunodeficiency 14 5.00 Very Low Very Low Very Low
Cirrhosis 10 5.00 Very Low Very Low Very Low
Disease 9 5.00 Very Low Very Low Very Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
Furthermore, blocking p90Rsk activity by over-expression of a catalytically inactive form of p90Rsk enhanced Fas-mediated cell death [61].
Gene_expression (expression) of p90Rsk associated with death
1) Confidence 0.30 Published 2003 Journal BMC Gastroenterol Section Body Doc Link PMC317301 Disease Relevance 0.75 Pain Relevance 0
Furthermore, blocking p90Rsk activity by over-expression of a catalytically inactive form of p90Rsk enhanced Fas-mediated cell death [61].
Gene_expression (expression) of p90Rsk associated with death
2) Confidence 0.26 Published 2003 Journal BMC Gastroenterol Section Body Doc Link PMC317301 Disease Relevance 0.75 Pain Relevance 0
In this study, we ask: Are activated forms of ERK, RSK, and CREB colocalized in the cortex and are they coordinately regulated by synaptic signals?
Gene_expression (forms) of RSK in cortex
3) Confidence 0.22 Published 2004 Journal J. Comp. Neurol. Section Abstract Doc Link 15389611 Disease Relevance 0 Pain Relevance 0
The four cytoplasmic proteins, S473p-PKB, p-S6K, p-S6 and p-NF?
Gene_expression (p-S6) of p-S6
4) Confidence 0.01 Published 2008 Journal BMC Cancer Section Body Doc Link PMC2270852 Disease Relevance 0.88 Pain Relevance 0

General Comments

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