INT121796

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Context Info
Confidence 0.78
First Reported 2004
Last Reported 2010
Negated 6
Speculated 2
Reported most in Body
Documents 92
Total Number 97
Disease Relevance 23.18
Pain Relevance 10.53

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

Anatomy Link Frequency
neuronal 20
neurons 13
brain 4
striatum 4
NeuN 4
NeuN (Mus musculus)
Pain Link Frequency Relevance Heat
Calcitonin gene-related peptide 18 100.00 Very High Very High Very High
substance P 13 100.00 Very High Very High Very High
Hippocampus 575 99.60 Very High Very High Very High
ischemia 680 99.36 Very High Very High Very High
cerebral cortex 81 99.28 Very High Very High Very High
Anterior cingulate cortex 128 99.24 Very High Very High Very High
cytokine 94 99.04 Very High Very High Very High
Pyramidal cell 94 98.60 Very High Very High Very High
bDMF 78 96.08 Very High Very High Very High
Glutamate 175 95.84 Very High Very High Very High
Disease Link Frequency Relevance Heat
Ganglion Cysts 292 100.00 Very High Very High Very High
Generalized Anxiety Disorder 11 100.00 Very High Very High Very High
Cancer 81 99.86 Very High Very High Very High
Aids-related Complex 262 99.64 Very High Very High Very High
Brain Hemorrhage 219 99.36 Very High Very High Very High
Targeted Disruption 537 99.20 Very High Very High Very High
Status Epilepticus 77 98.64 Very High Very High Very High
Brain Injury 77 98.64 Very High Very High Very High
Convulsion 362 98.04 Very High Very High Very High
Apoptosis 158 98.00 Very High Very High Very High

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
Synaptophysin was diffusely positive in neuropil-like areas, and many tumor cells expressed NeuN.
Gene_expression (expressed) of NeuN in neuropil associated with cancer
1) Confidence 0.78 Published 2004 Journal Brain Pathol. Section Abstract Doc Link 15446592 Disease Relevance 0.45 Pain Relevance 0.16
No colocalization of these markers was found, thus supporting the hypothesis that neuronal differentiation (as marked by NeuN expression) is incompatible with continued proliferation of tumor cells, as well as normal neurons.
Gene_expression (expression) of NeuN in neurons associated with cancer
2) Confidence 0.78 Published 2004 Journal Brain Pathol. Section Abstract Doc Link 15446592 Disease Relevance 0.50 Pain Relevance 0.15
Primary antibodies used were: rabbit anti-GFP, 1:500 (Invitrogen; Eugene, OR), guinea pig anti-SP; 1:500 (Neuromics; Edina, MN), rabbit anti-CGRP, 1:500 (Immunostar; Hudson, WI), mouse anti-NeuN. 1:500 (Chemicon; Temecula, CA), mouse anti-GFAP, 1:400 (Sigma; St.
Gene_expression (anti) of NeuN associated with calcitonin gene-related peptide and substance p
3) Confidence 0.65 Published 2010 Journal Mol Pain Section Body Doc Link PMC2900238 Disease Relevance 0 Pain Relevance 0.20
Some NeuN-positive neuronal cells expressed BDNF at 30 days after NMDA injection (Figure 4B).
Gene_expression (expressed) of NeuN in neuronal
4) Confidence 0.64 Published 2009 Journal Molecular Vision Section Body Doc Link PMC2664844 Disease Relevance 0 Pain Relevance 0
The expression of NeuN is similar to that previously reported in the mammalian retina [31-35].
Gene_expression (expression) of NeuN in retina
5) Confidence 0.63 Published 2008 Journal Molecular Vision Section Body Doc Link PMC2519030 Disease Relevance 0.35 Pain Relevance 0
Immunostaining for neuron-specific antigen (NeuN immunostaining) of sections from the HCl/HBr treated mice confirmed the normal appearance of morphology within neuronal populations in each brain region examined.
Gene_expression (immunostaining) of NeuN in neuronal
6) Confidence 0.62 Published 2009 Journal Neuropsychiatric Disease and Treatment Section Body Doc Link PMC2695230 Disease Relevance 0.56 Pain Relevance 0.17
Numerous GFP-positive cells expressed NeuN, betaIII-tubulin, or 68 kD neurofilaments.
Gene_expression (expressed) of NeuN
7) Confidence 0.62 Published 2006 Journal J. Neurobiol. Section Abstract Doc Link 16838369 Disease Relevance 0 Pain Relevance 0.09
The density of newborn mature neurons was calculated by dividing the number of BrdU+ cells expressing NeuN by SGZ-GCL sectional area (mm2).
Gene_expression (expressing) of NeuN in NeuN
8) Confidence 0.59 Published 2010 Journal PLoS ONE Section Body Doc Link PMC3004858 Disease Relevance 0 Pain Relevance 0
The percentage of BrdU-positive cells expressing the neuronal marker NeuN (?
Gene_expression (expressing) of NeuN in neuronal
9) Confidence 0.58 Published 2010 Journal PLoS ONE Section Body Doc Link PMC2921340 Disease Relevance 0.31 Pain Relevance 0
To determine the phenotype of the BrdU-positive cells in the OB, BrdU/NeuN double-labeling was performed using rat anti-BrdU (1?
Gene_expression (/) of NeuN
10) Confidence 0.58 Published 2010 Journal PLoS ONE Section Body Doc Link PMC2921340 Disease Relevance 0 Pain Relevance 0
To determine the phenotype of the BrdU-positive cells in the OB, BrdU/NeuN double-labeling was performed using rat anti-BrdU (1?
Gene_expression (double) of NeuN
11) Confidence 0.58 Published 2010 Journal PLoS ONE Section Body Doc Link PMC2921340 Disease Relevance 0 Pain Relevance 0
BrdU-positive cells were examined for co-labeling with NeuN (10–20 cells per animal, n?
Gene_expression (labeling) of NeuN
12) Confidence 0.58 Published 2010 Journal PLoS ONE Section Body Doc Link PMC2921340 Disease Relevance 0 Pain Relevance 0
Concomitant with Prox1 expression, the mature pan-neural marker NeuN begins to be expressed at 1 week after transplantation and levels increased up to 4 weeks following transplantation (Figure 6F, H).
Gene_expression (expressed) of NeuN in neural
13) Confidence 0.57 Published 2010 Journal PLoS ONE Section Body Doc Link PMC3013129 Disease Relevance 0.37 Pain Relevance 0.04
The density of NeuN-positive neurons in the CP drastically decreased by 13 days after RU-486 injection (F6,54?
Gene_expression (neurons) of NeuN in neurons
14) Confidence 0.56 Published 2009 Journal PLoS ONE Section Body Doc Link PMC2613534 Disease Relevance 0 Pain Relevance 0.14
To quantify neuronal activation in the ACC by sexual attraction, we used double immunostaining of Fos and NeuN (Fig. 2A and 2B).
Gene_expression (immunostaining) of NeuN in neuronal associated with anterior cingulate cortex
15) Confidence 0.52 Published 2009 Journal Mol Brain Section Body Doc Link PMC2685783 Disease Relevance 0.07 Pain Relevance 0.32
Sections were then used for c-Fos and/or NeuN immunoreactivity.
Gene_expression (immunoreactivity) of NeuN
16) Confidence 0.52 Published 2009 Journal Mol Brain Section Body Doc Link PMC2685783 Disease Relevance 0 Pain Relevance 0.08
At 28 days following the insult, 76 ± 8 % and 87 ± 11 % BrdU-incorporated cells expressed NeuN in the SVZ and striatum after intranasal administration of TGF-?
Gene_expression (expressed) of NeuN in striatum
17) Confidence 0.51 Published 2008 Journal BMC Neurosci Section Body Doc Link PMC2637876 Disease Relevance 0.31 Pain Relevance 0.09
There was, however, a significant increase in the production of BrdU/NeuN-positive cells in the CBD group (CBD vs.
Gene_expression (production) of NeuN
18) Confidence 0.50 Published 2010 Journal Cell Commun Signal Section Body Doc Link PMC2898685 Disease Relevance 0.40 Pain Relevance 0
LacZ staining and co-expression with NeuN-immunoreactivity (NeuN-ir) was observed by microscopy and described by an operator blind to the genotypes.


Gene_expression (expression) of NeuN
19) Confidence 0.50 Published 2008 Journal Behav Brain Funct Section Body Doc Link PMC2531118 Disease Relevance 0.38 Pain Relevance 0.06
While it takes weeks under normal conditions for newborn cells to mature into neurons in the adult DG [59], approximately 10% of our grafted cells express the pan-neural marker NeuN by 7 days following transplantation.
Gene_expression (express) of NeuN in neural
20) Confidence 0.50 Published 2010 Journal PLoS ONE Section Body Doc Link PMC3013129 Disease Relevance 0.43 Pain Relevance 0.03

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