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Context Info
Confidence 0.01
First Reported 2004
Last Reported 2004
Negated 0
Speculated 0
Reported most in Abstract
Documents 1
Total Number 1
Disease Relevance 0.25
Pain Relevance 0.20

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

cytoplasm (CACNA1A, CAV2) nucleus (CACNA1A, CAV2) plasma membrane (CACNA1A, CAV2)
small molecule metabolic process (CACNA1A) Golgi apparatus (CAV2) mitochondrion organization (CAV2)
CACNA1A (Homo sapiens)
CAV2 (Homo sapiens)
CACNA1A - V1696I (1) CACNA1A - K1336E (1)
Pain Link Frequency Relevance Heat
Migraine 2 86.92 High High
addiction 1 71.20 Quite High
Disease Link Frequency Relevance Heat
Migraine With Aura 2 86.92 High High
Disease 1 85.32 High High

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
Here we investigated not only whether FHM1 mutations K1336E (KE), W1684R (WR), and V1696I (VI) can affect Cav2.1 channel function but focused on the important question whether mutation-induced changes on channel gating depend on the beta-subunit isoform.
FHM1 (K1336E, V1696I, W1684R) Regulation (affect) of Cav2
1) Confidence 0.01 Published 2004 Journal J. Biol. Chem. Section Abstract Doc Link 15448138 Disease Relevance 0.25 Pain Relevance 0.20

General Comments

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