INT12192

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Context Info
Confidence 0.39
First Reported 1992
Last Reported 1992
Negated 0
Speculated 0
Reported most in Abstract
Documents 1
Total Number 1
Disease Relevance 0.45
Pain Relevance 0.64

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

biosynthetic process (Gpt) cellular_component (Gpt) biological_process (Gpt)
cytoplasm (Gpt)
Anatomy Link Frequency
liver 2
Gpt (Rattus norvegicus)
Pain Link Frequency Relevance Heat
Bile 1 100.00 Very High Very High Very High
Glutamate 1 100.00 Very High Very High Very High
Paracetamol 14 93.92 High High
Disease Link Frequency Relevance Heat
Hepatotoxicity 5 99.24 Very High Very High Very High
Parkinson's Disease 1 84.80 Quite High
Injury 2 25.04 Quite Low
Hypoxia 2 25.00 Low Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
Hepatotoxicity was evident from the nearly complete interruption of bile secretion, a marked release of enzymes [glutamate-pyruvate transaminase (GPT), lactate dehydrogenase (LDH)] in the perfusate, a depletion of hepatic glutathione and an accumulation of calcium in the liver.
Negative_regulation (interruption) of Localization (secretion) of GPT in liver associated with glutamate, bile and hepatotoxicity
1) Confidence 0.39 Published 1992 Journal Biochem. Pharmacol. Section Abstract Doc Link 1632830 Disease Relevance 0.45 Pain Relevance 0.64

General Comments

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