INT122000

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Context Info
Confidence 0.23
First Reported 2004
Last Reported 2004
Negated 0
Speculated 0
Reported most in Abstract
Documents 1
Total Number 1
Disease Relevance 0.11
Pain Relevance 0.28

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

plasma membrane (PTGS1, TNF) nuclear envelope (PTGS1) small molecule metabolic process (PTGS1)
aging (PTGS1) Golgi apparatus (PTGS1) endoplasmic reticulum (PTGS1)
Anatomy Link Frequency
monocytes 3
PTGS1 (Homo sapiens)
TNF (Homo sapiens)
Pain Link Frequency Relevance Heat
cINOD 2 99.90 Very High Very High Very High
dexamethasone 1 91.92 High High
aspirin 2 90.84 High High
COX2 1 25.00 Low Low
Disease Link Frequency Relevance Heat
Necrosis 1 57.04 Quite High
Cancer 1 56.68 Quite High

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
The results suggest that in human endotoxin-stimulated monocytes, NSAIDs can enhance TNFalpha expression through inhibition of cyclooxygenase and the resulting decrease in prostanoid biosynthesis.
Negative_regulation (inhibition) of cyclooxygenase in monocytes Positive_regulation (enhance) of Gene_expression (expression) of TNFalpha in monocytes associated with cinod
1) Confidence 0.23 Published 2004 Journal Eur. J. Pharmacol. Section Abstract Doc Link 15464057 Disease Relevance 0.11 Pain Relevance 0.28

General Comments

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