INT122051

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Context Info
Confidence 0.48
First Reported 2004
Last Reported 2010
Negated 0
Speculated 0
Reported most in Body
Documents 17
Total Number 20
Disease Relevance 9.11
Pain Relevance 3.38

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

cell adhesion (ROM1)
Anatomy Link Frequency
joint 2
shoulder 2
knee 2
dorsal 1
plasma 1
ROM1 (Homo sapiens)
Pain Link Frequency Relevance Heat
Pain 179 99.90 Very High Very High Very High
Osteoarthritis 139 97.52 Very High Very High Very High
Inflammation 26 91.76 High High
rheumatoid arthritis 9 90.68 High High
shoulder pain 7 89.88 High High
fibrosis 86 85.04 High High
imagery 33 73.76 Quite High
cytokine 15 72.12 Quite High
Arthritis 7 71.96 Quite High
Analgesic 10 69.04 Quite High
Disease Link Frequency Relevance Heat
Intervertebral Disk Degeneration 12 99.96 Very High Very High Very High
Neck Pain 15 99.90 Very High Very High Very High
Bursitis 54 99.48 Very High Very High Very High
Myalgia 6 99.36 Very High Very High Very High
Osteoarthritis 45 97.52 Very High Very High Very High
Aids-related Complex 5 96.88 Very High Very High Very High
Injury 46 95.12 Very High Very High Very High
Adhesions 16 93.40 High High
Shoulder Impingement Syndrome 16 93.28 High High
Ulcers 1 92.48 High High

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
RESULTS: Globally, the TLIF and revision ALIF procedures significantly reduced ROM and NZ compared with that of the intact condition.
Negative_regulation (reduced) of ROM
1) Confidence 0.48 Published 2010 Journal J Neurosurg Spine Section Body Doc Link 20043769 Disease Relevance 0 Pain Relevance 0
In the early stage of disc degeneration, ROM increases while in the late stage of disc degeneration, ROM decreases.
Negative_regulation (decreases) of ROM associated with intervertebral disk degeneration
2) Confidence 0.43 Published 2010 Journal J Orthop Surg Res Section Body Doc Link PMC2993665 Disease Relevance 0.38 Pain Relevance 0
These findings suggest that antioxidant supplementation was helpful in reducing the elevations in plasma CK activity and MS, with little impact on MIF and ROM loss.
Negative_regulation (loss) of ROM in plasma associated with myalgia
3) Confidence 0.42 Published 2004 Journal Int J Sport Nutr Exerc Metab Section Abstract Doc Link 15467097 Disease Relevance 0.43 Pain Relevance 0
In subjects who had positive results, ROM for both tests was significantly reduced compared to ROM on the contralateral side and ROM in subjects who had negative results.
Negative_regulation (reduced) of ROM
4) Confidence 0.41 Published 2009 Journal J Manipulative Physiol Ther Section Body Doc Link 19362228 Disease Relevance 0.07 Pain Relevance 0
At normal speed, the substantial modification of the locomotor pattern was linked to the adaptation of the lower-limb segment coordination and to the loss of ROM.
Negative_regulation (loss) of ROM in limb segment
5) Confidence 0.37 Published 2007 Journal Exp Brain Res Section Abstract Doc Link 16915399 Disease Relevance 0.41 Pain Relevance 0.25
Patients were able to produce an efficient pattern despite a reduction of the ROM of the forefoot.
Negative_regulation (reduction) of ROM
6) Confidence 0.37 Published 2007 Journal Exp Brain Res Section Abstract Doc Link 16915399 Disease Relevance 0.43 Pain Relevance 0.25
Both unilateral and bilateral group, the ROM and NZ of flexion-extension and lateral bending were decreased significantly after transpedicle screw in comparison with intact status.
Negative_regulation (decreased) of ROM in lateral
7) Confidence 0.37 Published 2010 Journal J Orthop Surg Res Section Body Doc Link PMC2993665 Disease Relevance 0 Pain Relevance 0
The bilateral group's ROM (-1.7 ± 0. 8) of axial rotation was decreased significantly after transpedicle screw insertion procedure in comparison with the unilateral group (-0.2 ± 0.1).
Negative_regulation (decreased) of ROM
8) Confidence 0.37 Published 2010 Journal J Orthop Surg Res Section Abstract Doc Link PMC2993665 Disease Relevance 0.06 Pain Relevance 0
The bilateral group's ROM of axial rotation was decreased significantly after transpedicle screw insertion (-1.7 ± 0.8 vs -0.7 ± 0.4, p < 0.05) procedure in comparison with the unilateral group.
Negative_regulation (decreased) of ROM
9) Confidence 0.37 Published 2010 Journal J Orthop Surg Res Section Body Doc Link PMC2993665 Disease Relevance 0 Pain Relevance 0
Clohisy et al. [38] found no ROM differences between FAI and non-symptomatic hips, whereas Philippon et al. [34] reported significantly reduced ROM in injured hips for all directions.
Negative_regulation (reduced) of ROM in hips
10) Confidence 0.35 Published 2010 Journal BMC Musculoskelet Disord Section Body Doc Link PMC2942800 Disease Relevance 0.15 Pain Relevance 0.06
Although the glenohumeral joint synovial capsule is often involved in adhesive capsulitis, most of the significant loss of ROM results from pathology in structures outside of the glenohumeral joint synovial capsule (e.g., coracohumeral ligament, rotator interval, subscapularis muscle, and subacromial bursa) [18].
Negative_regulation (loss) of ROM in joint associated with bursitis
11) Confidence 0.35 Published 2008 Journal BMC Musculoskelet Disord Section Body Doc Link PMC2257930 Disease Relevance 0.85 Pain Relevance 0.08
It aims to release the structures that cause significant loss of ROM of the shoulder.
Negative_regulation (loss) of ROM in shoulder
12) Confidence 0.35 Published 2008 Journal BMC Musculoskelet Disord Section Body Doc Link PMC2257930 Disease Relevance 0.89 Pain Relevance 0.22
At the first year follow up a decrease of ROM in the ankle was noted, particularly in dorsal flexion, weakness and hypotrophy of the leg were seen.


Negative_regulation (decrease) of ROM in dorsal
13) Confidence 0.30 Published 2008 Journal J Orthop Traumatol Section Body Doc Link PMC2656963 Disease Relevance 0.69 Pain Relevance 0.15
Persons wishing to delay surgery should be referred to physical therapy to address age-related impairments, deficits in KOS-ADLS scores and loss of knee extension ROM.
Negative_regulation (loss) of ROM in knee
14) Confidence 0.27 Published 2010 Journal BMC Musculoskelet Disord Section Body Doc Link PMC2877653 Disease Relevance 0.40 Pain Relevance 0.23
Physicians and clinicians should be aware that potentially modifiable factors, such as knee ROM, can be addressed to potentially postpone the need for TKA.
Negative_regulation (addressed) of ROM in knee
15) Confidence 0.27 Published 2010 Journal BMC Musculoskelet Disord Section Body Doc Link PMC2877653 Disease Relevance 0.34 Pain Relevance 0.16
Post-operative arthrofibrosis with decreased ROM may also increase the risk for knee deterioration especially in the patellofemoral joint.
Negative_regulation (decreased) of ROM in joint
16) Confidence 0.21 Published 2008 Journal J Orthop Surg Section Body Doc Link PMC2430704 Disease Relevance 0.70 Pain Relevance 0.24
This painful condition leads decreases in muscle strength and range of motion (ROM) of the shoulder which adversely affect the patients' quality of life.3
Negative_regulation (decreases) of ROM in shoulder associated with pain
17) Confidence 0.14 Published 2010 Journal Clinics (Sao Paulo) Section Body Doc Link PMC2972614 Disease Relevance 1.04 Pain Relevance 0.64
Of these assessments, 6 revealed increased ROM during drug intervention while 1 revealed a decreased ROM.
Negative_regulation (decreased) of ROM
18) Confidence 0.11 Published 2007 Journal Radiat Oncol Section Abstract Doc Link PMC1891306 Disease Relevance 0.62 Pain Relevance 0.31
Of these, three had measurable improvement of 24, 31 and 73% while one had a decline in total ROM of 8%.
Negative_regulation (decline) of ROM
19) Confidence 0.11 Published 2007 Journal Radiat Oncol Section Body Doc Link PMC1891306 Disease Relevance 0.32 Pain Relevance 0.09
Ongoing cervical pain and reduced range of motion (ROM) associated with chronic WAD constitute both a prognostic and a therapeutic dilemma.
Negative_regulation (reduced) of ROM associated with pain and neck pain
20) Confidence 0.07 Published 2004 Journal BMC Musculoskelet Disord Section Body Doc Link PMC356919 Disease Relevance 1.34 Pain Relevance 0.73

General Comments

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