INT122058

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Context Info
Confidence 0.39
First Reported 2004
Last Reported 2004
Negated 0
Speculated 0
Reported most in Abstract
Documents 1
Total Number 2
Disease Relevance 0.18
Pain Relevance 1.63

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

oxidoreductase activity (VKORC1) endoplasmic reticulum (VKORC1)
VKORC1 (Homo sapiens)
Pain Link Frequency Relevance Heat
Paracetamol 18 97.16 Very High Very High Very High
Analgesic 4 71.24 Quite High
Disease Link Frequency Relevance Heat
Poisoning 2 96.68 Very High Very High Very High

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
NAPQI also inhibited VKOR, but at higher concentrations.
Negative_regulation (inhibited) of VKOR
1) Confidence 0.39 Published 2004 Journal Thromb. Haemost. Section Abstract Doc Link 15467911 Disease Relevance 0.09 Pain Relevance 0.82
Unexpectedly, N-acetylcysteine was found to inhibit VKOR activity at concentrations that are obtained during rescue therapy of paracetamol intoxication.
Negative_regulation (inhibit) of VKOR associated with paracetamol and poisoning
2) Confidence 0.39 Published 2004 Journal Thromb. Haemost. Section Abstract Doc Link 15467911 Disease Relevance 0.10 Pain Relevance 0.81

General Comments

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